Soft Tissue Characterization of the Knee Region
Conditions
Brief summary
Knee osteoarthritis is a common cause of disability, affecting more than 650 million people aged 40 and over worldwide in 2020. To relieve pain and improve mobility, some patients use knee orthoses . However, the effectiveness of these devices is not universally agreed upon, and users report widely varying levels of satisfaction. This study aims to understand how the body responds to these orthoses from a biomechanical perspective, and in particular to quantify the interactions with soft tissues (skin, adipose tissue and muscles). To better understand this interaction, the authors propose to characterize soft tissue behavior on an individual basis using an indentation technique. In practice, this involves pressing on the soft tissues with an ultrasound probe to measure their stiffness at the interface between the leg and the orthosis.
Interventions
OTHERKnee indentation
we push the soft tissue in the indentation zone with an instrumented elastographic probe, allowing to assess force vs tissue thickness.
Sponsors
Centre de recherche Inria de l'Université de Rennes
Lyon 1 University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Participant whose skin is intact on at least one of the two legs, in the tested area. Participant able to understand simple instructions, conditioning guidelines, and to provide informed consent. Adult over the age of 50, not under guardianship. Participant having signed the study participation consent form. Non-inclusion Criteria Persons covered by articles L. 1121-5 to L. 1121-8 and L. 1122-1-2 (minors, protected adults, etc.) Skin lesions, inflammation, or acute local pain on the tested leg. Neuromuscular pathology preventing controlled muscle contraction. Joint pain preventing the performance of everyday activities (e.g., walking, rising from a chair, climbing stairs…).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| force-displacement curves | through study completion, an average of 1 year | Using the force below and displacement below, this a construction of the relative displacement with regard to the applied force |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Indentation force (N) | through study completion, an average of 1 year | Force being applied by the indenter on the zone to be indented |
| Displacement (mm) | through study completion, an average of 1 year | using motion capture, this is the assessment of the relative displacement of the probe with regard to the resting position during an indentation |
| Height (m) | through study completion, an average of 1 year | Height of the subject, measured with a standard ruler |
| Weight (kg) | through study completion, an average of 1 year | measured with a standard scale |
| Muscle activity (mV) | through study completion, an average of 1 year | from the main flexors and extensors of the thigh, using EMGs |
Countries
France
Outcome results
None listed