Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07638319

Acronym

BTCPARPBV

Enrollment

Registered

2026-06-10

Start date

2025-12-01

Completion date

2028-12-01

Last updated

2026-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Grafting, Alveolar Bone Loss, Tooth Extraction, Tooth Extraction Site Healing

Keywords

Beta-tricalcium phosphate, Alveolar ridge preservation, Bone volume, Implant site development, Socket preservation, Ridge augmentation, Tooth extraction, Volumetric Changes

Brief summary

The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using β-TCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing. The main questions it aims to answer are: Does β-TCP improve ridge preservation compared with natural healing? Researchers will compare β-TCP grafted sockets to natural healing sockets to see if β-TCP better preserves ridge volume. Participants will: Have a tooth indicated for extraction. Be assigned to either β-TCP or natural healing. Undergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.

Interventions

DEVICENeocement Inject P® (Beta-Tricalcium Phosphate)

After tooth extraction the socket will be grafted with Neocement Inject P® (Beta-Tricalcium Phosphate).

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* 18 years or older * Acceptance of informed consent * Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion criteria

* Presence of active infection or severe inflammation in the intervention zone * Relevant medical history that contraindicates implant surgery * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%) * Uncontrolled and /or untreated periodontal disease * Heavy smokers (more than 10 cigarettes per day) * Immunosuppression

Design outcomes

Primary

Measure	Time frame	Description
Change in alveolar ridge volume after tooth extraction	From enrollment to the end of treatment at 6 months	Change in alveolar ridge volume after tooth extraction on sockets grafted with Beta-Tricalcium Phosphate

Countries

Portugal

Contacts

CONTACTAngel Lobito, Masters' in Dentistry

alobito@egasmoniz.edu.pt00351924347050

STUDY_DIRECTORJoão Botelho, PhD in Biomedical Sciences

Clinical Research Unit (CRU), Egas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health & Science

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 12, 2026