The Effect of Respiratory Muscle Training on Cognitive Performance

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07637331

Enrollment

Registered

2026-06-09

Start date

2026-03-27

Completion date

2027-04-01

Last updated

2026-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Muscle Training

Brief summary

Determine if exercise training for the respiratory muscles improves cognitive performance during periods when breathing against a resistance.

Interventions

DEVICEInspiratory muscle training

8 weeks of active or sham inspiratory muscle training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* 18-40 years old * Body mass index \<30 kg/m2 * Naïve to IMT * \>75% of predicted forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC) (FEV1/FVC) * Access to smart phone or tablet with internet

Exclusion criteria

* Diagnosed: * Cardiovascular disease * Respiratory disease (including asthma) * Metabolic disease * Currently pregnant * Unable to adhere to the IMT protocol * Answering 'yes' to any of the questions on page one of the PAR-Q+ * Abnormal cognition assessed via the Montreal Cognitive Assessment (score of 25 or less) * Self-reported color blindness * Significant acute or chronic medical, neurologic, or illness in the participant that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability of the participant to complete the study, and/or compromise the objectives of the study

Design outcomes

Primary

Measure	Time frame	Description
Diaphragm thickness	Baseline and after 8 weeks of training	ultrasound measurements of diaphragm thickness
Cognitive performance	Baseline and after 8 weeks of training	CAAPES performance with the higher percentage correct corresponding to a better performance.

Secondary

Measure	Time frame	Description
Dyspnea	Baseline and after 8 weeks of training	Measure of breathing discomfort and pleasantness using a visual analog scale, the higher the value the more discomfort and unpleasant the subject's breathing is.

Countries

United States

Contacts

CONTACTBlair Johnson

bj33@iu.edu812-855-8699

PRINCIPAL_INVESTIGATORBlair Johnson, PhD

Indiana University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 27, 2026