Delayed Intracranial Hemorrhages in Patients With Minor Head Injury on Anticoagulant or Dual Anti-platelet Therapy

Delayed Intracranial Hemorrhages in Patients With Minor Head Injury on Anticoagulant or Dual Anti-platelet Therapy: Role of Repeat Head CT Scan in the Emergency Department. A Single-center Retrospective Observational Study.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07631936

Enrollment

1000

Registered

2026-06-08

Start date

2024-01-01

Completion date

2026-12-01

Last updated

2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhage Brain

Brief summary

Retrospective observational study on a cohort of 2 years to evaluate the incidence of brain hemorrhage present at control head CT scan executed after routine 24h observation period of ED stay in patients with minor head injury on anticoagulant therapy or DAPT with an initial negative head CT.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 18 * Minor head injury (GCS ≥ 13) * Current anticoagulant or dual antiplatelet therapy * ED admission for head injury

Exclusion criteria

* Not meeting the full set of inclusion criteria.

Design outcomes

Primary

Measure	Time frame	Description
To evaluate the incidence of brain hemorrhage present at control head CT scan executed after routine 24h observation period of ED stay in patients with minor head injury on anticoagulant therapy or DAPT with an initial negative head CT.	From enrollment to the end of ED observation at 24 hours	To evaluate the incidence of brain hemorrhage present at control head CT scan executed after routine 24h observation period of ED stay in patients with minor head injury on anticoagulant therapy or DAPT with an initial negative head CT.

Secondary

Measure	Time frame	Description
To determine the incidence of a major brain hemorrhage (requiring neurosurgical intervention) or hospital admission at repeat (24h) head CT scan in patients with an initial negative CT.	From enrollment to the end of ED observation at 24 hours	To determine the incidence of a major brain hemorrhage (requiring neurosurgical intervention) or hospital admission at repeat (24h) head CT scan in patients with an initial negative CT.

Countries

Italy

Outcome results