Anterior Cruciate Ligament Injury, Knee Joint
Conditions
Keywords
Anterior Cruciate Ligament Reconstruction, Preoperative Rehabilitation, Functional Outcomes, Neuromuscular Training, Strength Training, Balance Training, Single-Leg Hop Test, IKDC, KOOS
Brief summary
Anterior cruciate ligament (ACL) rupture is a common knee injury that frequently requires surgical reconstruction and extensive postoperative rehabilitation. Preoperative rehabilitation (prehabilitation) has been suggested as a strategy to optimize physical function before surgery and enhance postoperative recovery. This prospective randomized controlled trial aims to evaluate the effectiveness of a structured six-week prehabilitation program on functional outcomes following anterior cruciate ligament reconstruction (ACLR). Seventy-six participants with complete ACL rupture scheduled for primary ACLR were randomly assigned to either a prehabilitation group or a control group receiving standard preoperative care. The prehabilitation program consisted of progressive strengthening exercises, neuromuscular training, balance exercises, and functional movement training performed three times per week. Functional outcomes were assessed at baseline, immediately before surgery, and at three and six months postoperatively using the International Knee Documentation Committee (IKDC) Score, the Knee Injury and Osteoarthritis Outcome Score (KOOS), the Tegner Activity Scale, and the Single-Leg Hop Test. The study aims to determine whether preoperative prehabilitation predicts improved postoperative functional recovery after ACL reconstruction and to provide evidence for optimizing rehabilitation strategies in this patient population.
Detailed description
Anterior cruciate ligament (ACL) rupture is one of the most common knee injuries among physically active individuals and is frequently managed with ACL reconstruction (ACLR). Despite advances in surgical techniques and postoperative rehabilitation, many patients continue to experience deficits in strength, neuromuscular control, and functional performance after surgery. Optimizing physical function before surgery may contribute to improved postoperative recovery. Preoperative rehabilitation, commonly referred to as prehabilitation, has been proposed as a strategy to enhance muscle strength, improve neuromuscular function, and prepare patients for postoperative rehabilitation. However, evidence regarding its effectiveness in improving functional outcomes following ACL reconstruction remains limited. This prospective randomized controlled trial was designed to evaluate the impact of a structured six-week prehabilitation program on postoperative functional outcomes in individuals undergoing primary ACL reconstruction. Participants diagnosed with complete ACL rupture and scheduled for surgery were randomly assigned to either a prehabilitation group or a control group receiving standard preoperative care. The prehabilitation program included progressive strengthening exercises, neuromuscular training, balance training, and functional movement exercises performed three times weekly under supervision. Participants were followed throughout the perioperative period and during postoperative rehabilitation. Functional recovery was evaluated using validated patient-reported outcome measures and functional performance assessments at predefined time points before and after surgery. The study seeks to determine whether preoperative prehabilitation contributes to superior functional recovery and improved return-to-activity outcomes following ACL reconstruction.
Interventions
BEHAVIORALPreoperative Prehabilitation Program
A structured six-week preoperative rehabilitation program including progressive strengthening exercises, neuromuscular training, balance exercises, and functional movement training performed three times per week prior to anterior cruciate ligament reconstruction.
Participants receive routine standard preoperative care without structured prehabilitation intervention.
Sponsors
Beni-Suef University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
No masking is used in this study because the nature of the prehabilitation intervention does not permit blinding of participants or study personnel.
Intervention model description
Participants will be randomized to either a prehabilitation group or a control group and will remain in their assigned group throughout the study.
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Male and female patients diagnosed with complete anterior cruciate ligament (ACL) rupture. * Patients scheduled for primary anterior cruciate ligament reconstruction (ACLR). * Age between 18 and 45 years. * Medically fit to participate in a preoperative rehabilitation program. * Willingness to participate in the study and provide informed consent. * Ability to attend preoperative rehabilitation sessions regularly.
Exclusion criteria
* Previous surgery on the affected knee. * Multiligament knee injuries other than isolated ACL rupture. * Associated fractures around the knee joint. * Severe meniscal or cartilage injuries requiring specific surgical management that may affect rehabilitation outcomes. * Neurological disorders affecting lower limb function or balance. * Systemic diseases that may interfere with rehabilitation (e.g., uncontrolled diabetes, severe cardiovascular disease). * Inability to comply with the rehabilitation protocol or follow-up schedule. * Refusal or inability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| International Knee Documentation Committee (IKDC) Score | Baseline, preoperatively, 3 months postoperatively, and 6 months postoperatively | The IKDC subjective knee form will be used to assess symptoms, function, and sports activity in patients undergoing ACL reconstruction. Higher scores indicate better knee function. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Knee Injury and Osteoarthritis Outcome Score (KOOS) | Baseline, preoperatively, 3 months postoperatively, and 6 months postoperatively | The KOOS is a patient-reported outcome measure used to assess knee-related symptoms, pain, activities of daily living, sports function, and quality of life following ACL reconstruction. |
| Tegner Activity Scale | Baseline, preoperatively, 3 months postoperatively, and 6 months postoperatively | The Tegner Activity Scale is used to evaluate the level of physical activity and return to sports participation in patients after ACL reconstruction. |
| Single-Leg Hop Test | Baseline, preoperatively, 3 months postoperatively, and 6 months postoperatively | The Single-Leg Hop Test is used to assess functional performance, limb symmetry, and dynamic stability following ACL reconstruction. |
Countries
Egypt
Contacts
PRINCIPAL_INVESTIGATORSahar M Abdelmutilibe, PHD
Faculty of Physical Therapy, Beni Suef University, Cairo, Egypt
Outcome results
None listed