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DDK Acoustic Analysis and Swallowing Indicators

Acoustic Analysis of Performance in Diadochokinetic (DDK) Tasks and Swallowing Function Indicators Among Adults Across Different Age Groups

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07626749
Acronym
AAP-DDK
Enrollment
720
Registered
2026-06-04
Start date
2026-06-15
Completion date
2030-04-09
Last updated
2026-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysphagia, Swallowing Function, Swallowing Risk

Keywords

Dysphagia, Swallowing Function, diadochokinetic, Acoustic Analysis, Repetitive Saliva Swallowing Test, EAT-10, Older Adults

Brief summary

This study examines whether simple speech tasks and a swallowing screening test can help identify swallowing risk in adults of different ages. Participants will complete basic questions, a swallowing self-assessment, a saliva swallowing test, and short voice recordings of rapid syllables. The study is non-invasive, takes about 75 minutes, and may help develop an easy, low-cost screening tool for early swallowing problems.

Detailed description

This is a cross-sectional observational study examining the relationship between diadochokinetic (DDK) speech performance and swallowing function in community-dwelling adults aged 18 years and older. Participants will complete a single study visit, during which demographic and health-related information will be collected, the EAT-10 swallowing self-assessment will be administered, the Repetitive Saliva Swallowing Test (RSST) will be performed, and short DDK speech recordings of /pa/, /ta/, and /ka/ will be obtained in a quiet setting. Acoustic features will be extracted from the recordings and analyzed together with RSST and EAT-10 results to explore age-related differences and to develop a predictive screening model for swallowing risk. All data will be de-identified, securely stored, and retained according to study requirements.

Interventions

None listed

Sponsors

Kaohsiung Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* 1.Community-dwelling adults aged 18 years or older, with no upper age limit. * 2.Ability to communicate in Mandarin or Taiwanese and understand the study procedures. * 3.Willingness to provide written informed consent. * 4 .Ability to complete the DDK tasks and RSST.

Exclusion criteria

* 1.Presence of acute respiratory infection, upper respiratory inflammation, or other acute conditions that may significantly affect speech or swallowing. * 2.Impaired consciousness, significant cognitive deficits, or inability to understand the study procedures. * 3.Recent surgery or radiotherapy involving the oral cavity or pharynx that affects speech or swallowing. * 4.Severe hearing impairment that prevents understanding of instructions. * 5.Any other condition deemed unsuitable for participation by the investigators.

Design outcomes

Primary

MeasureTime frameDescription
Repetitive Saliva Swallowing Test ClassificationDay 1Classification of swallowing function based on the Repetitive Saliva Swallowing Test (RSST). Participants will be classified as having normal RSST performance if they complete greater than or equal to 3 swallows in 30 seconds, and abnormal RSST performance if they complete fewer than 3 swallows in 30 seconds.

Secondary

MeasureTime frameDescription
Eating Assessment Tool-10 Total ScoreDay 1Total score on the Eating Assessment Tool-10 (EAT-10), a 10-item self-report questionnaire used to assess swallowing-related symptoms. The total score ranges from 0 to 40, where higher scores indicate worse swallowing-related symptoms. A score of 3 or higher suggests possible swallowing difficulty.
Diadochokinetic Speech RateDay 1Rate of repeated diadochokinetic speech productions of /pa/, /ta/, and /ka/. The rate will be reported as syllables per second.
Diadochokinetic Speech Fundamental FrequencyDay 1Fundamental frequency (F0) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Fundamental frequency will be reported in Hertz (Hz).
Diadochokinetic Speech First Formant FrequencyDay 1First formant frequency (F1) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. F1 reflects the first resonance frequency of the vocal tract and will be reported in Hertz (Hz).
Diadochokinetic Speech Second Formant FrequencyDay 1Second formant frequency (F2) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. F2 reflects the second resonance frequency of the vocal tract and will be reported in Hertz (Hz).
Diadochokinetic Speech JitterDay 1Jitter extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Jitter reflects short-term cycle-to-cycle variability in fundamental frequency and will be reported as a percentage.
Diadochokinetic Speech ShimmerDay 1Shimmer extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. Shimmer reflects short-term variability in voice amplitude and will be reported in decibels (dB).
Diadochokinetic Speech Harmonics-to-Noise RatioDay 1Harmonics-to-noise ratio (HNR) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. HNR reflects the ratio of periodic harmonic energy to noise energy in the voice signal and will be reported in decibels (dB).
Diadochokinetic Speech Root Mean Square AmplitudeDay 1Root mean square (RMS) amplitude extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. RMS amplitude reflects the average acoustic energy of the speech signal and will be reported in normalized amplitude units.
Diadochokinetic Speech Zero-Crossing RateDay 1Zero-crossing rate (ZCR) extracted from repeated diadochokinetic (DDK) speech recordings of /pa/, /ta/, and /ka/. ZCR reflects the rate at which the speech signal changes sign over time and will be reported as the number of zero crossings per second.

Countries

Taiwan

Contacts

CONTACTHUNG C F Kaohsiung Medical University, MASTER
gabino00076@gmail.com+8867-3121101
STUDY_CHAIRGUO L Y Professor and Dean of the College of Health Sciences, Departme, Ph. D.

Department of Sports Science, Kaohsiung Medical University, Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 5, 2026