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Early Bone Loss in Dental Implants

Retrospective Evaluation of Early Bone Loss in Dental Implants

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07625813
Acronym
Early Bone Los
Enrollment
256
Registered
2026-06-04
Start date
2025-01-15
Completion date
2026-02-15
Last updated
2026-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implant, Marginal Bone Loss

Keywords

Dental implants, Early bone loss, Marginal bone loss, Peri-implant bone loss, Implant-supported prosthesis

Brief summary

This retrospective observational study aims to evaluate early marginal bone loss around dental implants using panoramic radiographs. Radiographic records of patients who underwent mandibular dental implant surgery and implant-supported prosthetic rehabilitation will be reviewed. Marginal bone loss will be measured on the mesial and distal aspects of each implant at final restoration delivery and at follow-up periods after prosthetic loading. The study will also assess patient-, implant-, and prosthesis-related factors associated with marginal bone loss.

Interventions

None listed

Sponsors

Abant Izzet Baysal University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Individuals older than 18 years * Patients with mandibular dental implants * Availability of panoramic radiographs obtained after implant surgery and after prosthetic loading * Panoramic radiographs suitable for radiographic evaluation * Visibility of the mandibular inferior cortex and mental foramen on panoramic radiographs * Systemically healthy individuals

Exclusion criteria

* Low-quality panoramic radiographs * Missing follow-up radiographs * Presence of systemic diseases or conditions that may affect bone metabolism

Design outcomes

Primary

MeasureTime frameDescription
Change in Marginal Bone Loss Over TimeAt final restoration delivery, 6 months, 18 months, and 60 months after prosthetic loadingMarginal bone loss will be assessed on panoramic radiographs by measuring the linear distance from the implant platform to the nearest supporting crestal bone on the mesial and distal aspects of each implant. Mesial, distal, and mean marginal bone loss values will be recorded in millimeters.

Secondary

MeasureTime frameDescription
Effect of implant length on mean marginal bone lossUp to 60 months after prosthetic loadingThe effect of implant length on mean marginal bone loss will be evaluated using regression analysis. Implant length will be recorded in millimeters from patient records and implant system information. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Effect of implant diameter on mean marginal bone lossUp to 60 months after prosthetic loading.The effect of implant diameter on mean marginal bone loss will be evaluated using regression analysis. Implant diameter will be recorded in millimeters from patient records and implant system information. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Effect of abutment height on mean marginal bone lossUp to 60 months after prosthetic loading.The effect of abutment height on mean marginal bone loss will be evaluated using regression analysis. Abutment height will be recorded in millimeters from prosthetic records. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Effect of implant-tooth distance on mean marginal bone lossUp to 60 months after prosthetic loading.The effect of implant-tooth distance on mean marginal bone loss will be evaluated using regression analysis. Implant-tooth distance will be measured on panoramic radiographs as the horizontal distance between the implant and the adjacent natural tooth when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Effect of implant-implant distance on mean marginal bone lossUp to 60 months after prosthetic loading.The effect of implant-implant distance on mean marginal bone loss will be evaluated using regression analysis. Implant-implant distance will be measured on panoramic radiographs as the horizontal distance between adjacent implants when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Effect of emergence profile angle on mean marginal bone lossUp to 60 months after prosthetic loading.The effect of emergence profile angle on mean marginal bone loss will be evaluated using regression analysis. Emergence profile angle will be recorded in degrees when applicable. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Mean marginal bone loss according to implant placement levelUp to 60 months after prosthetic loading.Mean marginal bone loss will be compared according to implant placement level. Implant placement level will be categorized as crestal, subcrestal, or supracrestal according to the vertical position of the implant platform relative to the crestal bone level. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Mean marginal bone loss according to prosthetic restoration typeUp to 60 months after prosthetic loading.Mean marginal bone loss will be compared according to prosthetic restoration type. Prosthetic restoration type will be categorized according to the type of implant-supported prosthetic rehabilitation, including single crown, fixed partial prosthesis, splinted crowns, full-arch fixed restoration, or removable prosthesis. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.
Mean marginal bone loss according to opposing arch conditionUp to 60 months after prosthetic loading.Mean marginal bone loss will be compared according to opposing arch condition. Opposing arch condition will be categorized according to the dentition or prosthetic status of the opposing arch. Mean marginal bone loss will be calculated by averaging mesial and distal marginal bone loss measurements for each implant.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 5, 2026