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Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors

Study on the Effect of Hyperbaric Oxygen Intervention on Relieving Sports Fatigue of Sailors

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07625696
Enrollment
16
Registered
2026-06-04
Start date
2026-06-30
Completion date
2026-10-29
Last updated
2026-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elite Male Sailing Athletes

Brief summary

1. Research Purpose Intensive training often causes autonomic nerve imbalance, poor microcirculation and slow fatigue recovery in elite sailing athletes. This study adopted 1.3 ATA mild hyperbaric oxygen with 28% oxygen concentration for a 6-week intervention. It aimed to explore whether mild hyperbaric oxygen can improve athletes' autonomic nerve function, microcirculation and fatigue-related biochemical indicators. Meanwhile, it intended to estimate the effect size, provide basis for future large-scale formal trials, and optimize fatigue recovery strategies for sailing athletes and other endurance athletes. 2. Study Population A total of 16 elite male sailing athletes were enrolled and randomly divided into two groups with 8 participants in each group. Inclusion criteria: aged over 18 years; holding national first-class athlete certificate or above; participating in systematic sailing training at least 5 times a week with more than 5 years of professional training experience. Those with cardiovascular diseases, absolute contraindications to hyperbaric oxygen, training suspension due to injury and other ineligible conditions were excluded. 3. Primary Outcome Measures Autonomic nerve function: Heart rate variability (HRV) indicators were tested to observe whether hyperbaric oxygen balances sympathetic and parasympathetic nerves and relieves training-induced autonomic disorder. Microcirculation function: Measured muscle microcirculation blood flow velocity, capillary perfusion and thermal stimulation microvascular reserve capacity to evaluate the improvement of peripheral blood circulation. Fatigue and biochemical biomarkers: Routine blood indexes: red blood cell, hemoglobin, white blood cell; Exercise injury and metabolic indexes: creatine kinase (CK), blood urea nitrogen (BUN), testosterone and cortisol; Oxidative stress indexes: malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), to assess the body's oxidation-antioxidant status, inflammation level and fatigue recovery degree.

Interventions

DEVICEMild Hyperbaric Oxygen Therapy

Participants receive mild hyperbaric oxygen therapy (mHBOT) in a hyperbaric chamber at 1.3 atmospheres absolute (ATA) with 28% oxygen concentration, for 60 minutes per session, 5 sessions per week over 6 weeks. All participants continue their standard sailing training regimen throughout the study.

Sponsors

Shanghai Research Institute of Sports Science
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Male elite sailing athletes aged 18-35 years * Holding a national first-class athlete certificate or above * With at least 5 years of professional sailing training experience * Engaging in regular sailing training ≥ 5 times per week * Voluntarily sign the informed consent form

Exclusion criteria

* \- Presence of cardiovascular, respiratory, or neurological diseases * Absolute contraindications to hyperbaric oxygen therapy * Current injury or illness requiring medical treatment or training suspension * Use of any medications or supplements that may affect fatigue recovery or autonomic function * Participation in other concurrent recovery interventions during the study

Design outcomes

Primary

MeasureTime frame
Change in Heart Rate Variability (HRV)Baseline (Week 0), Post-intervention (Week 6)

Contacts

CONTACTjin yu
759559257@qq.com+86 18101732823

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 31, 2026