Tooyh Discoloration
Conditions
Keywords
Dental bleaching At-home bleaching Carbamide peroxide WID OHIP-14, CIELAB, Oral health-related quality of life
Brief summary
This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported outcomes. Changes in tooth color will be assessed using CIELAB parameters (L\*, a\*, b\*) and the Whiteness Index for Dentistry (WID), while quality of life will be evaluated using the OHIP-14 questionnaire.
Detailed description
Tooth bleaching is a widely used minimally invasive treatment for improving dental aesthetics. Objective evaluation of color changes is essential and is commonly performed using the CIELAB color space and derived indices such as the Whiteness Index for Dentistry (WID). This study will be designed as a prospective, non-randomized before-after clinical trial to evaluate the clinical efficacy of an at-home dental bleaching protocol and its effect on tooth color. The protocol will consist of the at-home application of 16% carbamide peroxide delivered through custom trays for six weeks, with one daily application lasting 90 minutes. The primary objectives of this study will be to quantify color changes and bleaching effectiveness, as well as to evaluate oral health-related quality of life and the subjective impact of treatment. Additional analyses will include a detailed assessment of the behavior of the individual CIELAB parameters and their variation during treatment, the analysis of correlations between WID and the individual color parameters, and the evaluation of oral health-related quality of life using the OHIP-14 questionnaire.
Interventions
DRUGCarbamide peroxide 16%
Blanqueamiento dental domiciliario utilizando peróxido de carbamida al 16% aplicado mediante férulas individualizadas durante seis semanas, con una aplicación diaria de 90 minutos. Los cambios en el color dentario se evaluarán mediante mediciones espectrofotométricas de los parámetros CIELAB (L\*, a\*, b\*) y del Índice de Blancura para Dentistas (WID). La calidad de vida relacionada con la salud oral también se evaluará mediante el cuestionario OHIP-14.
Sponsors
University of Valencia
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
All participants will receive the same at-home dental bleaching treatment using 16% carbamide peroxide delivered through custom trays for six weeks. Color changes and oral health-related quality of life will be evaluated before and after treatment.
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age between 20 and 40 years * Healthy gums and periodontal condition * No oral diseases * No previous dental bleaching treatment * No restorations in anterior teeth * Ability to attend follow-up visits * Willingness to follow the study instructions
Exclusion criteria
* Smoking * Pregnancy * Breastfeeding * Medical conditions that could affect bleaching treatment * Use of medications that could interfere with bleaching treatment * Inability to comply with scheduled appointments
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Whiteness Index for Dentistry (WID) | Baseline to 6 weeks | Change in dental whiteness measured using the Whiteness Index for Dentistry (WID) calculated from the CIELAB color parameters (L\*, a\*, b\*) obtained by spectrophotometry before and after at-home dental bleaching treatment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in CIELAB color parameters (L*, a*, b*) | Baseline, 3 weeks, and 6 weeks | Objective color changes measured using spectrophotometric evaluation of the CIELAB color parameters (L\*, a\*, b\*) during at-home dental bleaching treatment. |
| Oral Health-Related Quality of Life (OHIP-14) | Baseline and 6 weeks | Oral health-related quality of life will be assessed using the OHIP-14 questionnaire at baseline and after 6 weeks of at-home dental bleaching. Changes in OHIP-14 scores will be used to evaluate the impact of treatment on patients' oral health-related quality of life. |
Contacts
CONTACTJosé Amengual-Lorenzo, DDS, PhD
CONTACTRubén Agustín-Panadero, DDS, PhD
PRINCIPAL_INVESTIGATORJosé Amangual-Lorenzo, DDS, PhD
Universitat de València
STUDY_CHAIRRubén Agustín-Panadero, DDS, PhD
Universitat de València
Outcome results
None listed