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Comparison of First and Second Capillary Blood Drops for Blood Glucose Measurement

Comparison of Capillary Blood Sampling Techniques for Blood Glucose Measurement in People With Diabetes: An Experimental Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07624266
Enrollment
64
Registered
2026-06-03
Start date
2025-02-01
Completion date
2025-12-30
Last updated
2026-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Keywords

Blood glucose monitoring, Capillary blood sampling, First blood drop, Finger squeezing, Glucometer, Self-monitoring of blood glucose

Brief summary

This study aimed to evaluate the effects of different capillary blood sampling techniques on blood glucose measurement results in people with diabetes. Blood glucose measurements obtained from the first and second capillary blood drops after antiseptic application were compared. In addition, measurements obtained with and without finger squeezing were evaluated. The findings may contribute to improving standardization in capillary blood glucose monitoring procedures and reducing unnecessary repeated finger punctures in clinical practice.

Detailed description

This methodological and experimental study evaluated whether different capillary blood sampling techniques influence blood glucose measurement results in people with diabetes. The study compared glucose measurements obtained from the first and second capillary blood drops and also evaluated measurements performed with and without finger squeezing under standardized clinical conditions. The findings are expected to contribute to the standardization of capillary blood glucose monitoring procedures and improve clinical practice by reducing unnecessary repeated finger punctures and enhancing participant comfort.

Interventions

OTHERCapillary Blood Sampling Techniques

Blood glucose measurements obtained from the first and second capillary blood drops and measurements performed with and without finger squeezing were compared using the same glucometer device under standardized clinical conditions.

Sponsors

Ordu University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Aged 18 years or older * Diagnosed with diabetes mellitus * Provided written and verbal informed consent to participate in the study * Eligible for blood glucose measurement after at least 6 hours of fasting * No condition preventing capillary blood sampling from the fingertip * Physically and mentally able to undergo the measurement procedures specified in the study

Exclusion criteria

* Presence of a physical disability or deformity affecting fingertip blood glucose measurement * Presence of coagulation disorders (e.g., hemophilia) or severe medical conditions affecting blood sampling * Use of steroids within the previous 24 hours that could affect blood glucose levels * Presence of physical or mental conditions limiting compliance with study procedures * Inability or unwillingness to provide informed consent

Design outcomes

Primary

MeasureTime frameDescription
Difference between blood glucose measurements obtained with and without finger squeezingDay 1Comparison of blood glucose values obtained from capillary blood samples collected with and without finger squeezing. Blood glucose measurements were obtained consecutively during a single study visit (Day 1), first from a capillary blood sample collected without finger squeezing and subsequently from a capillary blood sample collected with finger squeezing during the same blood sampling and measurement session
Difference between blood glucose values obtained from the first and second capillary blood drops following antiseptic applicationDay 1Comparison of blood glucose values obtained from the first and second capillary blood drops after antiseptic application. The first and second blood drop measurements were obtained consecutively during the same capillary blood sampling and measurement session.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 4, 2026