Depression, Anxiety and Sleep in Parkinson's Disease

Assessment of Depression , Anxiety and Sleep Disorders in Patients With Idiopathic Parkinson's Disease

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07622303

Enrollment

100

Registered

2026-06-03

Start date

2026-06-01

Completion date

2027-05-31

Last updated

2026-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's Disease

Brief summary

This study aims to assess the prevalence and severity of depression, anxiety, and sleep disorders among patients with idiopathic Parkinson's disease. The study will evaluate the relationship between neuropsychiatric symptoms and disease characteristics in order to improve early recognition and patient quality of life.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

A-Inclusion Criteria: 1. Patients diagnosed with idiopathic Parkinson's disease according to the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease (Postuma et al., 2015). 2. Age ≥ 50 years. 3. Ability to understand and respond to questionnaires and rating scales. 4. Ability and willingness to provide informed consent. B-

Exclusion criteria

1. Patients with atypical parkinsonism. 2. Patients with a history of other major neurological disorders (e.g., stroke, Alzheimer's disease, multiple sclerosis). 3. Patients with severe cognitive impairment or dementia that prevents reliable completion of rating scales. 4. Patients with a current diagnosis of severe psychiatric disorders unrelated to 5-Parkinson's disease (e.g., schizophrenia, bipolar disorder). 6-Patients with unstable medical conditions. 7-Patients unable or unwilling to provide informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Assessment of Depression Severity in Patients with idiopathic Parkinson's Disease	Baseline assessment during study enrollment.	Depression severity measured using the Hamilton Depression Rating Scale (HAM-D). Scores range from 0 to 52, with higher scores indicating more severe depression.
Assessment of Anxiety Severity in Patients with idiopathic Parkinson's Disease	Baseline	Anxiety severity measured using the Hamilton Anxiety Rating Scale (HAM-A). Scores range from 0 to 56, with higher scores indicating more severe anxiety.
Assessment of Sleep Disturbance in Patients with idiopathic Parkinson's Disease	Baseline	Sleep disturbance measured using the Parkinson's Disease Sleep Scale (PDSS). Higher scores indicate better sleep quality and fewer sleep-related symptoms.

Outcome results