Crohn Disease (CD), Ulcerative Colitis (UC)
Conditions
Keywords
Crohn; ulcerative colitis, LRG, endoscopic remission, endoscopic activity, PRO, quality of life
Brief summary
Prospectively study the correlation between Leucine-rich α2-glycoprotein (LRG) and clinical/endoscopic/histological disease activity in patients with inflammatory bowel disease (IBD) in Europe.
Interventions
DIAGNOSTIC_TESTLeucine-rich α2-glycoprotein
Leucine-rich α2-glycoprotein measurement
Sponsors
Imelda GI Clinical Research Center
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. ≥18 years 2. Patient with confirmed diagnosis of IBD 3. Patient with planned endoscopy (ileocolonoscopy for Crohn's disease (CD)/ulcerative colitis (UC) or sigmoidoscopy for UC) for the assessment of endoscopic disease activity according to routine practice 4. willing to provide informed consent
Exclusion criteria
1. Patient with IBD unspecified 2. Patient with ileo- or colostomy 3. Patient with total colectomy 4. Women that are pregnant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between LRG serum level and endoscopic disease activity in CD and UC | Day 1 | Correlation between LRG serum level and endoscopic disease activity in CD and UC |
Countries
Belgium
Contacts
CONTACTPeter Bossuyt
Outcome results
None listed