TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair

TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair: A Single-center Prospective Study.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07618884

Enrollment

Registered

2026-06-01

Start date

2025-04-15

Completion date

2026-09-01

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal Hernia, Inguinal Hernia Repair

Keywords

Inguinal hernia, Chronic postoperative inguinal pain, Trans rectus sheath extra-peritoneal procedure

Brief summary

Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role. The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.

Detailed description

This is a prospective cohort study

Interventions

PROCEDUREtrans rectus sheath extra-peritoneal procedure (TREPP)

The TREPP technique, a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults with primary unilateral or bilateral inguinal hernia

Exclusion criteria

* Strangulated hernias. * Severe comorbidities precluding surgery ((ASA Class IV,V)

Design outcomes

Primary

Measure	Time frame	Description
Recurrence rate	through study completion, an average of 1 year	Number and percentage of patients with recurrence of hernia after surgery

Secondary

Measure	Time frame	Description
Incidence of chronic postoperative inguinal pain	3 months after surgery	Number and percentage of patients with groin pain that lasts more than three months after inguinal hernia surgery

Countries

Egypt

Contacts

CONTACTMohamad Raafat, MD

mohamad_raafat10@yahoo.com0201067877622

CONTACTFaculty of Medicine-Assiut University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 2, 2026