Polyethylene Glycol, Residual Gastric Contents
Conditions
Keywords
residual gastric volume, miralax, polythylene glycol, gastric POCUS, pediatric, EGD, colonoscopy
Brief summary
The goal of this clinical trial is to assess differences in residual gastric volumes after stopping Miralax ingestion at different time points (2, 4, 6 hours) prior to anesthesia induction and compare it to the control (current institutional standard of care where no Miralax is given on the day of surgery).
Interventions
BEHAVIORALStopping Miralax ingestion 4 hours prior to anesthesia induction
Stopping Miralax ingestion 4 hours prior to anesthesia induction
BEHAVIORALStopping Miralax ingestion 6 hours prior to anesthesia induction
Stopping Miralax ingestion 6 hours prior to anesthesia induction
BEHAVIORALStopping Miralax ingestion 2 hours prior to anesthesia induction
Stopping Miralax ingestion 2 hours prior to anesthesia induction
BEHAVIORALControl
Miralax will not be given on the day of surgery
Sponsors
Stanford University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Masking description
The endoscopist, the anesthesiologist performing the gastric POCUS evaluation, the anesthesiologist, the research coordinator
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing both EGD and colonoscopy * Use of Miralax for cleanout * Patients \<19 years old
Exclusion criteria
* Patients with a history of delayed gastric emptying (eg diabetic, GLP-1 intake) * Patients with a history of gastric sleeve surgery * Use of Golytely for cleanout * Emergent EGD/colonoscopies * EGD/colonoscopies for foreign body removal and/or decompression * Known neurologic compromise * Presence of pre-existing ostomy, short bowel syndrome, gastric retention, intestinal obstruction, ileus, bowel perforation, toxic colitis, toxic megacolon, swallowing difficulties * Pre-existing electrolyte derangements * Allergy to Miralax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual gastric volume as measured by EGD | To be performed at the start of the EGD immediately after anesthesia induction. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Preoperative gastric POCUS volume assessment | Performed prior to anesthesia induction | — |
| Effectiveness of colonoscopy cleanout | Performed during the colonoscopy portion following upper GI endoscopy (EGD) | The effectiveness of colonoscopy cleanout will be assessed by the Boston Bowel Preparation Scale (BBPS). |
| Incidence of aspiration on induction and perioperative aspiration | On anesthesia induction | — |
Outcome results
None listed