Hemondynamic Changes in Spinal Anesthesia
Conditions
Keywords
Spinal ansethesia, Fractionated, Bolus
Brief summary
To assess hemodynamic changes with hyperbaric bupivacaine with spinal anesthesia
Detailed description
Assesment of hemodynamic changes like heart rate and blood pressure with hyperbaric bupivacaine in spinal anesthesia when given in fractionanted versus bolus dose manner
Interventions
In this group B spinal Anesthesia will be given in one single shot
Sponsors
Liaquat National Hospital & Medical College
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* ASA I and II * Adults 18 to 60 years of age of either gender * height from 160 to 182cm and BMI from 15 to 29.9kg/m2
Exclusion criteria
* ASA III and IV * Refusal of consent * any known renal, hepatic, cardiac or cerebrovascular disease * hypersensitivity to local anaesthetics drug * spinal deformity or any contra indications to spinal anesthesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean Arterial Pressure | Baseline and up to 120 minutes | Difference in mean arterial pressure between Group B and Group F |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hypotension and bradycardia | Baseline and up to 120 minutes | Incidence of hypotension and bradycardia after spinal Anesthesia between Group B and Group F |
| Requirement of vasopressors | Baseline and up to 120 minutes | Requirements of vasopressors if mean arterial pressure falls below 60mmHg during the procedure and up to 120 minutes |
Countries
Pakistan
Contacts
CONTACTUsama, MBBS
Outcome results
None listed