Breathing, Healthy, Lung Function Decreased, MRI Imaging
Conditions
Brief summary
This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy human subjects.
Interventions
DEVICEAirway Oscillometer
The termoflo c-100 Airwave Oscillometer System is intended to measure respiratory system impedance using the Forced Oscillation Technique (FOT).
DIAGNOSTIC_TESTPhase Resolved Functional Lung MRI
The Phase Resolved Functional Lung (PREFUL) MRI technique acquires images of the lung so that measures of ventilatory defect percentage can be calculated.
Sponsors
University of Rochester
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age 18 years or older * Ability to provide consent * Willingness to perform MRI and breathing test * Must be able to speak and understand English
Exclusion criteria
* Pregnant * Unable or willing to provide consent or perform the required maneuvers for testing.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oscillometer | Single measurement, approximately 1 day | The oscillometer will collect an airway impedance measurement which is made up of multiple variables. |
| Phase Resolved Functional Lung (PREFUL) MRI | Single measurement, approximately 1 day | PREFUL MRI will acquire images of the lungs and a measurement called the ventilatory defect percentage (or VDP) will be calculated. |
Countries
United States
Contacts
CONTACTPatrick Donohue, MD
Outcome results
None listed