Obesity, Sarcopenic Obesity
Conditions
Keywords
Ageing, Obesity, Physical performance, Visceral adiposity
Brief summary
Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people. To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.
Interventions
OTHERFitness tests and questionnaires
Anthropometric measurements, physical fitness tests and daily life questionnaires
Sponsors
Istituto Auxologico Italiano
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Obese elderly: Inclusion Criteria: * Both sexes * Body Mass Index \> 35 kg/m2 * Age \> 65 years * Hospitalized for a 3-week integrated metabolic rehabilitation program
Exclusion criteria
* Absence of signed informed consent Normal weight elderly: Inclusion Criteria: * Both sexes * Body Mass Index 20-25 kg/m2 * Age \> 65 years * Attendance of healthy lifestyle program in their home town
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Fat mass | Baseline | Fat mass as assessed by bioelectrical impedance |
| Lean mass | Baseline | Lean mass as assessed by bioelectrical impedance |
| Barthel Index | Baseline | Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100 |
| Handgrip test | Baseline | Score in kilograms (kg) using a hand dynamometer |
Countries
Italy
Contacts
CONTACTAlessandro Sartorio, MD
CONTACTLuca Grappiolo, Dr
Outcome results
None listed