Silicate-Added Beta-TCP in Fully Guided Immediate Implants in the Esthetic Zone

Evaluation of Silicate-Added Beta-Tricalcium Phosphate Putty in Fully-Guided Immediate Implants in the Esthetic Zone Using Customized Healing Abutment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07613320

Acronym

SA-TCP Implant

Enrollment

Registered

2026-05-29

Start date

2025-12-01

Completion date

2026-07-30

Last updated

2026-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Grafting, Customized Healing Abutment, Immediate Dental Implant Placement, Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement

Keywords

Immediate implant placement, Fully-guided surgery, Esthetic zone, Customized healing abutment, Si-β-TCP putty

Brief summary

This study aims to evaluate bone and soft tissue changes clinically and digitally after using a customized healing Abutment with or without silicate-added beta-tricalcium phosphate (Si-β-TCP) putty.

Detailed description

Fully guided immediate implant placement in the esthetic zone presents challenges related to soft tissue closure, jumping gap management, and peri-implant stability. The use of silicate-added β-TCP putty with customized healing abutments has been proposed to improve soft tissue healing and maintain peri-implant architecture.

Interventions

PROCEDURESilicate-added β-TCP putty for jumping gap grafting

Application of silicate-added beta-tricalcium phosphate putty in the jumping gap around fully-guided immediate implants placed in the esthetic zone, combined with provisional crown as a customized healing abutment to enhance peri-implant soft tissue healing and ridge preservation.

PROCEDUREConventional healing/ No graft

Standard fully-guided implant placement protocol without the use of bone graft material allowing natural healing of the jumping gap around immediately placed implants in the esthetic zone.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

1. Patients with non-restorable teeth in maxillary esthetic zone requiring dental extraction. 2. Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration. 3. Jumping gap more than 2mm. 4. Patients with good oral hygiene. 5. Patients willing to participate in the study's follow-up intervals.

Exclusion criteria

1. Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement. 2. Alcohol or drug abuse. 3. Smokers. 4. Patients with systemic diseases that absolutely contraindicate implant placement (bleeding disorders, immunosuppression,…etc.) 5. Pregnancy. 6. Patients with para-functional habits (bruxism and clenching). 7. Lack of motivation or inability to maintain good oral hygiene. \-

Design outcomes

Primary

Measure	Time frame	Description
Implant stability	Immediate post-operative, 3 months, and 6 months.	Implant stability will be evaluated using Osstell device based on resonance frequency analysis (ISQ values).
Hard Tissue (Peri-implant bone)	- Immediately after implant placement - 6 months after implant placement	Marginal bone loss will be assessed using CBCT measured in mm.

Secondary

Measure	Time frame	Description
Soft Tissue	Baseline, 1 month, 3 months, and 6 months.	Soft tissue contour and peri-implant tissue condition will be assessed using digital intraoral scanning (STL files) using superimposition and modified sulcus bleeding index (mSBI).

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 11, 2026