Cleaning and Shaping Only With Proper Coronal Seal, Necrotic Mature First Premolar, Regenerative Endodontic Treatment
Conditions
Keywords
Regenerative endodontic treatment, Regeneration in mature teeth, cleaning and shaping only concept
Brief summary
It was to compare clinically between the success of the primary endodontic treatment, regeneration, and only cleaning and shaping in necrotic mature first premolars with apical periodontitis
Detailed description
a- Fifty four patients were enrolled and screened for eligibility b- Participants were randomly assigned to three groups (n=18 per group) i- Group \[CRCT\]: Conventional root canal treatment (n=18) ii- Group \[REP\] : Regenerative endodontic treatment (REP) (n=18), cell homing technique was used , and MTA was placed 3mm into the canals , the access was sealed by light cured glass ionomer then composite iii- Group \[C.S\]: Only cleaning and shaping (n=18) the same steps of REP but without bleeding induction and MTA was placed 3mm into the canals , the access was sealed by light cured glass ionomer then composite
Interventions
OTHERcell homing
it is done by bleeding induction into the canals
PROCEDURECleaning and shaping only
proper canal disinfection and mechanical instrumentation followed by proper coronal seal
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Age: 20-50 years * Medically free * The patient should have the upper first premolar that needs endodontic treatment with apical periodontitis * Necrotic teeth * Participants were willing to commit to the entire period of the trial and agreed to sign the written consent after a full explanation of the study.
Exclusion criteria
* Symptomatic irreversible pulpitis * If the premolar is non restorable * If the premolar will need a post and core * Vertical root fracture * Open apex * Presence of any systemic disease or allergic reactions. * Vulnerable group; prisoners, pregnant females, mentally ill, etc…
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Resolution of the clinical and radiographic sign and symptoms | follow ups 3, 6 12 months | Clinically, no pain upon percussion or palpation, and no sinus tracts. Signs of radiographic bone healing it is going to be recorded as a yes/ no answer. No sign and symptoms= no pain upon percussion, palpation, and no sinus tract was observed Yes, there are signs and symptoms= that one or more of these criteria will be present \[ pain upon percussion, presence of a bulge upon palpation, sinus tract exists\] Radiographic healing will be assessed by 2 ways. 1. Qualitative test by using the Periapical Index Score; score 1 indicates bone healing, and score 5 indicates Severe apical periodontitis, with exacerbating features 2. Quantitative assessment measured the percent of lesion reduction using ImageJ software to measure the area of the lesion preoperatively and at follow-ups. This rule will be used: \[preoperative area - postoperative area\] / preoperative area = ... X100= ..% |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| restoring of the pulp vitality which will be recorded by electric pulp tester | 3,6,12 months | The reading at each follow-up will be a yes/ no answer Yes, there is sensation if the patient feels tingling while using the electric pulp tester No, no sensation if the patient didn't feel the tingling |
Countries
Egypt
Outcome results
None listed