Cardiac Abnormalities
Conditions
Brief summary
To collect data, written consent was obtained from the hospital and university administration. After receiving signed informed consent, the data was collected from cardiac patients.
Detailed description
The target population was adults between the ages of 35 and 65 years who were receiving outpatient care at a hospital or clinic with a diagnosis of either mild to moderate hypertension, mild to moderate alterations in lipid profile or pre-diabetes. To select potential participants from the study population, subjects with a medical history of diabetes, measuring fasting blood glucose, lipid profile and blood pressure were screened.Following screening, participants were divided evenly into three groups: experimental group (1, 2) and one control group. The participants were advised to take 2 slices of bread in breakfast. Individualized plans were given according to their nutrient requirements. A systematic communication plan was developed in order to follow up with participants on their daily consumption of the suggested watermelon rind-based bread through telephonic conversations. For continuous assistance there was a WhatsApp group set up where members may ask issues and get help. The follow up for patients were conducted every month; baseline and after 6 pre-treatments. Appointments for follow-up exams were done after every 15 days in order to track developments, anthropometric measurements were calculated every follow up and modify the dosage as necessary. The baseline and post study test was compared to test the hypothesis.
Interventions
DIETARY_SUPPLEMENTControl on Wheat bread
Participants were advised to take Two slices of wheat bread in breakfast for the duration of 02 months.
DIETARY_SUPPLEMENTExperimental G1 on WRB
Participants were advised to take 2 slices of Watermelon rind-based bread in breakfast for the duration of 02 months.
DIETARY_SUPPLEMENTExperimental G2 on WRB
Group 2: Participants were advised to take 2 slices of Watermelon rind-based bread in breakfast for the duration of 02 months.
Sponsors
University of Lahore
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
35 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* The inclusion criterion was target adults with both gender aged 35-65 years. Adults with a diagnosis of mild to moderate hypertension Mild hypertension (140-159/90-99 mm Hg) Moderate hypertension (160-179/100-109 mm Hg) Adults having mild to moderate alterations in lipid profile Triglycerides: 150 to 499 mg/dL LDL-C levels: Mild Alteration (130 to 159 mg/dL) and Moderate Alteration (160 to 189 mg/dL) Adults with pre-diabetes (hbA1c= 5.6-6.4%)
Exclusion criteria
* Any person allergic to wheat. * Any person any person allergic to watermelon rind. * Any adult having pancreatitis and hepatitis. * Any adults having serious health conditions like cancer.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anthropometric Measurements | 60 days | for body mass index weight in kg and height in meters squared, were used to calculate changes in body size. |
| Lipid Profile | 60 days | Blood lipid profile was obtained using fasting blood samples to determine serum total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides were monitored pre and post intervention. |
| Blood pressure | 60 days | Blood pressure was checked using an automated sphygmomanometer. Sitting blood pressure was measured in two ways; systolic blood pressure and diastolic blood pressure after 5 minutes rest. For analysis, the average of the three readings were taken. |
Countries
Pakistan
Contacts
PRINCIPAL_INVESTIGATORMaria Aslam
University of Lahore
Outcome results
None listed