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Ultrasound Measurement of Skin-to-Epiglottis Distance for Prediction of Difficult Airway in Adult Patients

Ultrasound Measurement of Skin to Epiglottis Distance for Prediction of Difficult Airway in Adult Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07609147
Enrollment
300
Registered
2026-05-27
Start date
2026-07-01
Completion date
2026-12-04
Last updated
2026-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheal Diamater Measurement, Tracheal Intubation, Elective Surgery, Ultrasound Evaluation of Airway

Keywords

ultrasound, airway, epiglottis, Skin-to-Epiglottis Distance, Difficult Airway Prediction

Brief summary

This prospective observational study aims to evaluate the predictive value of ultrasound-measured skin to epiglottis distance for difficult airway in adult patients undergoing elective or emergency procedures requiring airway management. The correlation between ultrasound measurements and standard airway assessment parameters will be analyzed.

Detailed description

Airway management is a critical component of anesthesia and intensive care practice. Predicting difficult airway remains challenging with conventional bedside tests. Ultrasound has emerged as a non-invasive, bedside tool for airway assessment. This study aims to investigate the relationship between skin-to-epiglottis distance measured by ultrasound and difficult laryngoscopy/intubation. Secondary comparisons will include traditional airway assessment methods such as Mallampati score, thyromental distance, and neck circumference

Interventions

None listed

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* ≥18 yaş elective surgery

Exclusion criteria

* emergency surgery * head and neck surgery * pregnant patients

Design outcomes

Primary

MeasureTime frameDescription
Skin to epiglottis distancePreintubation (within 30 minutes before procedure)Distance measured via ultrasound in the anterior neck region

Secondary

MeasureTime frameDescription
Incidence of difficult laryngoscopy (Cormack-Lehane grade ≥ 3)During intubation procedure (intraoperative period)The proportion of patients with difficult laryngoscopy defined as Cormack-Lehane grade 3 or 4 during direct laryngoscopy.
Intubation Difficulty Score (IDS)During intubation procedureAssessment of intubation difficulty using the Intubation Difficulty Score based on number of attempts, operators, alternative techniques, glottic exposure, lifting force, external laryngeal pressure, and vocal cord position.
Correlation between ultrasound measurements and Mallampati scorePreoperative assessmentCorrelation between tracheal diameter and skin to epiglottis distance measured by ultrasound and preoperative Mallampati classification.
Skin-to-Epiglottis Distance Measured by UltrasoundImmediately before induction of anesthesiaSkin-to-epiglottis distance will be measured using ultrasound immediately before anesthesia induction. The distance is recorded in millimeters (mm) as a continuous variable. Larger values indicate a greater skin-to-epiglottis distance and may be associated with an increased likelihood of difficult laryngoscopy. This is not a scored scale; therefore, no predefined minimum or maximum score exists.Cormack-Lehane Grading System. Scores range from Grade I to Grade IV. Grade I indicates full visualization of the glottis (easier laryngoscopy), whereas Grade IV indicates that neither the glottis nor the epiglottis is visible (most difficult laryngoscopy). Higher grades indicate a worse airway view.

Countries

Turkey (Türkiye)

Contacts

CONTACTAlmıla G Pamuk, Doç. Dr.
gulsunp@yahoo.com9005335296325
CONTACTmuhammed r hız, research assistant
drrasithiz@gmail.com9005417800327
STUDY_DIRECTORAlmıla g Pamuk, Doç Dr.

Hacettepe Univercity

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 18, 2026