QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment

Diagnostic Performance of Smartphone, 3D Imaging, QLF-D, and ICDAS Clinical Criteria for Non-Cavitated Caries Activity Assessment in Post-Orthodontic Patients Under a Preventive Program

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07608471

Enrollment

Registered

2026-05-27

Start date

2026-07-21

Completion date

2027-04-22

Last updated

2026-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries Lesion Activity, Dental Caries, Post-Orthodontic Enamel Demineralization, White Spot Lesions

Keywords

Dental Caries, Dental Caries White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization

Brief summary

This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS clinical criteria for assessing non-cavitated caries lesion activity in post-orthodontic patients under a preventive follow-up program. Thirty participants aged 11 to 46 years with active initial caries lesions will be followed for three months. Clinical examinations, QLF-D imaging, smartphone photographs, and intraoral 3D scans will be obtained at baseline and follow-up visits combined with professional prophylaxis and oral hygiene reinforcement. The study will analyze changes in lesion activity, fluorescence parameters, and surface characteristics over time, as well as the agreement and diagnostic performance among the evaluated methods.

Detailed description

This prospective longitudinal observational study will evaluate the agreement and diagnostic performance of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS clinical criteria for assessing non-cavitated caries lesion activity in post-orthodontic patients. Participants presenting active initial caries lesions on vestibular tooth surfaces will undergo clinical examinations, QLF-D imaging, smartphone photographs, and intraoral 3D scans at baseline and during a three-month preventive follow-up program. Professional prophylaxis and oral hygiene reinforcement will be performed throughout the study period. Changes in clinical lesion activity, fluorescence parameters, and topographic characteristics will be analyzed to determine the monitoring capacity, agreement, and diagnostic performance of the evaluated methods. Patient acceptance of the diagnostic technologies will also be assessed.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

11 Years to 46 Years

Healthy volunteers

Inclusion criteria

* Participants aged 11 to 46 years * Completed fixed orthodontic treatment * Presence of at least four active non-cavitated caries lesions (ICDAS 1-3) * Lesions located on vestibular surfaces of anterior teeth and/or premolars * Ability to attend follow-up visits during the three-month study period * Signed informed consent and/or assent form

Exclusion criteria

* Systemic conditions affecting salivary flow or enamel structure * Extensive cavitated lesions requiring restorative treatment * Ongoing orthodontic treatment * Use of medications that significantly affect oral conditions * Inability to cooperate with imaging procedures or follow-up visits

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic Agreement Measured by Weighted Kappa Between ICDAS Clinical Assessment and QLF-D, Smartphone Photography, and Intraoral 3D Imaging for Non-Cavitated Caries Lesion Activity	Baseline, 3 months and 6 months	Diagnostic agreement among ICDAS clinical criteria, QLF-D fluorescence parameters, smartphone intraoral photographs, and intraoral 3D imaging for identifying active and inactive non-cavitated caries lesions in post-orthodontic patients.

Contacts

CONTACTAndrea Cortes, PhD

cortesandrea@unbosque.edu.co312 3654862

Outcome results