Tooth Extraction Site Healing
Conditions
Keywords
Socket preservation, autogenous dentin, tooth extraction, alveolar ridge augmentation
Brief summary
Tooth extraction leads to a substantial reduction in alveolar bone volume, with up to 25% loss within the first year and up to 40-60% within three years. This prospective randomized clinical study aims to compare four commonly used methods of alveolar ridge preservation, evaluating their effectiveness in maintaining bone volume for later prosthetic or implant rehabilitation. Alveolar dimensions will be measured using calibrated CBCT imaging pre-extraction and at six months post-extraction.
Detailed description
The study evaluates four different approaches to alveolar ridge preservation after tooth extraction. Eligible patients aged 18-70 years will undergo minimally traumatic extraction. Four treatment modalities will be compared: 1) Spontaneous healing secured with a stitch (control group), 2) Application of collagen sponge (Parasorb Cone, Resorba, Germany) secured with a stitch, 3) Application of a tricalcium phosphate xenograft (Poresorb TCP, Lasak, Czech Republic) covered with a collagen sponge (Parasorb Cone) and secured with a stitch. 4) Application of autogenous dentin, covered with a collagen sponge (Parasorb Cone) and secured with a stitch. Alveolar ridge dimensions will be measured on CBCT before extraction and again after six months. Primary outcomes include the absolute and relative change in ridge width and height at 1 mm, 3 mm, and 5 mm below the highest point of the alveolar bone as per Del Canto-Díaz, 2019. Patient factors (periodontal biotype, soft tissue phenotype, and vestibular thickness of the alveolar bone) will be recorded to allow subgroup analysis.
Interventions
Wound after the tooth extraction will be secured with a stitch without addition of any augmentation material.
Wound after the tooth extraction will be filled with a collagen sponge (Parasorb Cone, Resorba, Germany) and secured with a stitch.
Wound after the tooth extraction will be filled with tricalcium phosphate xenograft (Poresorb TCP, Lasak, Czech Republic), covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.
Wound after the tooth extraction will be filled with grounded autogenous dentin, covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.
Sponsors
Study design
Eligibility
Inclusion criteria
* 18-70 years * no active periodontitis * signed informed consent with participation in the study * need for extraction of teeth other than third molars * patients requesting only standard/reimbursed care
Exclusion criteria
* drug or alcohol abuse * ongoing chemotherapy * ongoing radiotherapy * pregnancy * ongoing treatment of osteoporosis or other biological treatment with MRONJ risk * low compliance * patients asking for premium care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alveolar bone width | 6 months | Absolute and relative change in the alveolar bone width at 1 mm, 3 mm, and 5 mm below the alveolar crest measured from CBCT imagery. |
Countries
Czechia
Contacts
University of Ostrava