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Intraoperative Lung Mechanics Changes During HoLEP Surgery

Evaluation of Intraoperative Driving Pressure and Static Lung Compliance Changes in Holmium Laser Enucleation of Prostate (HoLEP) Surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07607704
Enrollment
45
Registered
2026-05-26
Start date
2026-05-15
Completion date
2026-08-31
Last updated
2026-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Driving Pressure, Holmium Laser Enucleation of the Prostate, Lung Protective Ventilation

Brief summary

This study aims to evaluate changes in driving pressure and static lung compliance during HoLEP surgery and to investigate their relationship with surgical and perioperative factors. This study is observational, and no changes will be made to the patients' current treatment processes.

Interventions

PROCEDUREHoLEP surgery

All parameters used in the study are part of routine clinical practice. No additional intervention or examination will be performed

Sponsors

Ankara City Hospital Bilkent
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Male patients over 18 years of age * Patients scheduled for elective HoLEP surgery * Patients who provide written informed consent

Exclusion criteria

* Preoperative severe lung disease * Thoracic pathology that may affect mechanical ventilation * Conditions where spontaneous breathing cannot be suppressed * Missing data severe lung disease * Thoracic pathology that may affect mechanical ventilation * Conditions where spontaneous breathing cannot be suppressed * Missing data

Design outcomes

Primary

MeasureTime frameDescription
Change in intraoperative driving pressureMeasured at baseline after induction stabilization and every 30 minutes throughout the operationChange in intraoperative driving pressure
Change in static lung complianceMeasured at baseline after induction stabilization and every 30 minutes throughout the operationChange in static lung compliance

Countries

Turkey (Türkiye)

Contacts

CONTACTBetül Güven Aytaç, Assos prof
drbguven@hotmail.com905073578351

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 27, 2026