Dental Anesthesia
Conditions
Brief summary
The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.
Interventions
DEVICEddMRI
Dental MRI imaging
Sponsors
University of Minnesota
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult age 18 or older * Health status of American Society of Anesthesiologists (ASA) class 1 or 2 * Able to provide informed consent * Able to appear in person at OMRIC on the days indicated for the study
Exclusion criteria
* ASA class 3 or higher * Pregnant patients * Taking any medication that would affect pain perception or interact with local anesthetic * Allergic/history of adverse reaction to local anesthetic or any component in the local anesthetic * Paresthesia in the area of innervation of Cranial Nerve V3 * Active infection or abscess in the oral and maxillofacial region * History of temporomandibular disorder, maximum incisal opening less than 15mm * History of recent dental trauma (within the past 6 months) * Dental hypersensitivity * Claustrophobia and/or conditions of anxiety or motion disorder (for MRI purposes) * Metallic, electronic, or magnetic implants or devices classified as MR Unsafe or Conditional by the American College of Radiology * Unable to give informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient reported sensation - 5min | 5 minutes after the nerve block | Minimum value: No numbness Maximum value: Numb High scores mean a successful outcome for the block. |
| Patient reported sensation - 1 hour | within 1 hour of the nerve block | Minimum value: No numbness Maximum value: Numb High scores mean a successful outcome for the block. |
| Ability to sense light touch | within 1 hour of the nerve block | binary scale. Options are yes or no |
| Ability to sense pressure | within 1 hour of the nerve block | Minimum value: 1.65 Maximum value: 6.65 Low scores mean that the participant can sense more, and that the block was less effective |
| Ability to sense direction of touch (only if can sense VonFrey fibers) | within 1 hour of the nerve block | Patient reports direction of sensation (up/down/right/left). This is scored 5 times per site |
| Ability to distinguish sharp versus dull (only if can sense VonFrey fibers) | within 1 hour of the nerve block | Patient reports sharp versus dull sensation. This is scored 5 times per site |
Countries
United States
Contacts
CONTACTRachel Uppgaard, DDS, FACS
PRINCIPAL_INVESTIGATORRachel Uppgaard, DDS, FACS
University of Minnesota
Outcome results
None listed