Acute Kidney Injury (AKI)
Conditions
Keywords
Acute kidney injury, Blood pressure variability, Anesthesia induction period, Non-cardiac surgery
Brief summary
The goal of this multicenter retrospective cohort study aimed to explore the effect of BPV during anesthesia induction and surgery on the occurrence of postoperative AKI in non-cardiac surgery patients.
Interventions
None listed
Sponsors
Zhongda Hospital
Nanjing First Hospital, Nanjing Medical University
The First Affiliated Hospital of Anhui Medical University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Undergoing non-cardiac surgery； * Adult；
Exclusion criteria
* Undergoing urological surgeries that partially directly affect kidney function (including relief of urinary tract obstruction, nephrectomy, or kidney transplantation); * Surgery duration less than 60 minutes; * Weight \< 30 kg or BMI \> 35 kg/m2; * Patients who underwent reoperation within 7 days after surgery; * Surgeries not performed under general anesthesia; * ASA \> IV; * No serum creatinine measurement available within 6 months before surgery (baseline value) or within 7 days after surgery; * Preexisting renal dysfunction or a diagnosis of chronic kidney disease before surgery (creatinine \> 443 μmol/L); * No invasive blood pressure monitoring during the anesthesia induction period, or missing more than 25% of intraoperative invasive blood pressure data collection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| AKI | Within 7 days after surgery. | AKI diagnosed according to KDIGO criteria within 7 days after surgery was the primary outcome event. |
Countries
China
Outcome results
None listed