Acute Myocardial Infarction (AMI)
Conditions
Keywords
AMI, CMR
Brief summary
The goal of this observational study is to evaluate the clinical utility of cardiac magnetic resonance (CMR) in patients with acute myocardial infarction (AMI). This is a retrospective and prospective cohort study that has already enrolled a number of patients and will continue to enroll additional patients on a rolling basis. The main question it aims to answer is: How does CMR, performed acute phase, contribute to risk stratification, prognostic assessment, and long-term clinical management in patients with AMI? Participants who have had an AMI will undergo CMR within one week of symptom onset. After discharge, they will be regularly followed up at 1, 3, 6, 9, and 12 months, and then every 6 months thereafter. Clinical outcomes will be collected during each follow-up visit.
Detailed description
This is an ambispective observational cohort study. The study will include patients who have already undergone CMR examination and meet the eligibility criteria, as well as consecutively enrolled patients who will undergo CMR during the prospective study period.
Interventions
OTHERCardiac magnetic resonance imaging
Cardiovascular magnetic resonance imaging will be used to assess cardiac structure, function, myocardial injury, infarct size, late gadolinium enhancement, microvascular obstruction, and other CMR-derived parameters. This is an observational cohort study, and no diagnostic test or treatment will be assigned by the investigators. CMR examinations have been or will be performed as part of routine clinical evaluation according to clinical indications.
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 years or older. * Patients diagnosed with acute myocardial infarction. * Patients who complete cardiovascular magnetic resonance imaging during the acute phase after symptom onset. * Patients with available clinical, CMR, and follow-up data.
Exclusion criteria
* History of previous myocardial infarction. * Severe renal insufficiency, defined as estimated glomerular filtration rate \<30 mL/min/1.73 m². * Presence of malignant tumors. * Poor CMR image quality unsuitable for analysis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major Adverse Cardiovascular Events (MACE) | through study completion, an average of 5 years | A composite of cardiovascular death, non-fatal myocardial infarction, unplanned coronary revascularization, and hospitalization for heart failure. Assessed from the date of index hospitalization through the end of follow-up. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac Magnetic Resonance (CMR) Imaging Parameters | Baseline | Presence of microvascular obstruction assessed by late gadolinium enhancement cardiovascular magnetic resonance imaging. |
Countries
China
Outcome results
None listed