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Effect of Two Different Irrigation Protocols and Activation Techniques on Postoperative Pain in Single-visit Endodontic Retreatment: Prospective Randomized Clinical Trial

Effect of Two Different Irrigation Protocols and Activation Techniques on Postoperative Pain in Single-visit Endodontic Retreatment: Prospective Randomized Clinical Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07599254
Enrollment
100
Registered
2026-05-20
Start date
2025-01-01
Completion date
2026-07-15
Last updated
2026-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apical Periodontitis

Brief summary

The relationship between different root canal irrigation techniques and pain after root canal treatment

Interventions

Root canal irrigation and postoperative pain

Sponsors

TC Erciyes University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* o Patients aged 18-60 years who are classified as medically healthy (ASA I or II), * Mature, single-rooted and canal teeth that had root canal treatment at least four years ago, * Teeth with previous root canal obturation 2-4 mm short of the apex, * Teeth that do not need periodontal and prosthetic treatment and whose periapical index score (PAI) is between 2 and 4 , * Teeth with single root and canal diagnosed with asymptomatic apical periodontitis, * Teeth suitable for rubber dam isolation.

Exclusion criteria

* o Patients who had taken analgesics, antibiotics, or corticosteroids within two weeks before root canal retreatment, * Teeth exhibiting periodontal attachment loss, * Presence of vertical root fractures, external root resorption, or perforations, * Teeth with retained broken instruments, * Non-restorable teeth, * Patients in the pregnancy and breastfeeding period.

Design outcomes

Primary

MeasureTime frame
Evaluation of the relationship between different root canal irrigation techniques and post-canal treatment pain using surveys.3-5 month

Countries

Turkey (Türkiye)

Contacts

CONTACTİPEK E ERASLAN AKYÜZ
ipekemamak@hotmail.com+905385591409

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 21, 2026