AML (Acute Myelogenous Leukemia
Conditions
Keywords
fitness, elderly, treatment
Brief summary
The study aims to evaluate the outcome of patients (overall survival) who received treatments commensurate with the proposed "Fitness" parameters compared to that of patients whose treatment differed either in the direction of greater or lesser aggressiveness than that proposed (evaluation of survival through Kaplan-Meier analysis and comparison with the log-rank test).
Detailed description
Evaluate adherence to SIE/SIES/GITMO criteria in therapeutic choice: assess the treatment actually received by the different patient groups and any deviations from those proposed (descriptive statistics) * Evaluate whether the SIE/SIES/GITMO criteria are still current after the introduction of new drugs (descriptive statistics) * Evaluate the treatment actually received by the different patient groups and any deviations from those proposed * Evaluate the possibility of potentially identifying new criteria to better define fitness categories in light of the therapy actually administered to the patient (descriptive statistics)
Interventions
OTHERFitness Categories: FIT, UNFIT and FRAIL
fitness categories and treatment received
Sponsors
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Acute Myeloid Leukemia Diagnosis no Acute Promyelocytic Leukemia aged more than 65 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival according to fitness categories and treatment received | "From enrollment to the end of treatment at 12 months" |
Countries
Italy
Outcome results
None listed