Comparative Evaluation of Alb PRF Versus Connective Tissue Graft in Reconstruction of Deficient Interdental Papilla

Evaluation of Albumin Platelet-Rich Fibrin Versus Subepithelial Connective Tissue Graft in Interdental Papilla Reconstruction: a Randomized Controlled Clinical Trial

Status

Not yet recruiting

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07597135

Enrollment

Registered

2026-05-19

Start date

2026-06-20

Completion date

2028-12-20

Last updated

2026-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deficient Interdental Papilla

Keywords

interdental papilla

Brief summary

This study will evaluate the efficacy of Alb PRF membrane in comparison to a subepithelial connective tissue graft in the reconstruction of interdental papillae.

Detailed description

the reconstruction will be done using the Hans Taki surgical technique, while Alb PRF will be used as a membrane.

Interventions

BIOLOGICALAlbumin (5% serum-protein solution containing immunoglobulins)

a variation of PRF done by heating up to 75 degree then mixed with the remaining prf to get membrane

BIOLOGICALconnective tissue graft

subepithelial connective tissue graft

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* inter dental papilla deficincy

Exclusion criteria

* smokers

Design outcomes

Primary

Measure	Time frame
papillary height measured from apical part of contact point to tip of papilla (CP-TP)	from enrollment, 3 months, 6months, 9months, 12months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 20, 2026