The Effect of Detrusor Underactivity in Determining Outcomes After Transurethral Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07596537

Enrollment

Registered

2026-05-19

Start date

2026-05-01

Completion date

2026-12-01

Last updated

2026-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Detrusor Underactivity, Transurethral Resection of the Prostate (TURP)

Brief summary

The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients presenting with chronic urinary retention. The main questions it aims to answer are: Will they restore spontaneous voiding? They will be divided into 2 comparative groups (each group 45 patients) based on detrusor contractility. * Group (A) consists of patients with normal detrusor (bladder contractility index more than 100). * Group (B) consists of patients with underactive detrusor (bladder contractility index less than 100).

Interventions

PROCEDUREtransurethral resection of Prostate

Standard TURP

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age: more than 50-year-old * Chronic urinary retention secondary to BPH * Prostate size Above 30 and less than 100gm

Exclusion criteria

* Prostate size over 100 gm and less than 30 gm * Prostatic carcinoma * Urinary bladder carcinoma * Acute urinary retention * Urethral stricture. * Previous bladder, urethral or prostate surgery. * Acute urinary tract infection. * Neurogenic bladder

Design outcomes

Primary

Measure	Time frame	Description
Restore spontaneous voiding	3 months	All the included patients in this study are urethral catheter-dependant pre-operatively and have very bad voiding parameters. we will assess how they will benefit after TURP by regaining spontaneous voiding without the need for urethral catheters any more.

Secondary

Measure	Time frame	Description
Flow rate improvement	3 months	uroflowmetry will be done to all patients 3 months post operative and results will be compared
Post voiding residual urine volume decrease	3 months	Post voiding residual urine volume will be calculated using ultrasound and results will be compared

Contacts

CONTACTSamir Sherif Rizkallah, MBBCH

150278@med.asu.edu.eg+201226846005

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 21, 2026