tDCS and the Gaze Cueing Effect

Influence of Transcranial Direct Current Stimulation Applied to the Right Orbitofrontal Cortex on Gaze and Arrow Cueing Effects

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07592559

Enrollment

Registered

2026-05-18

Start date

2022-06-02

Completion date

2022-12-08

Last updated

2026-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congruency, Cues Type, SOA, tDCS

Keywords

transcranial direct current stimulation, gaze cueing effect, orbitofrontal cortex

Brief summary

This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.

Detailed description

This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.To examine the distinct functions of the OFC in processing social versus non-social stimuli, participants were randomly assigned to one of three tDCS groups: anodal, cathodal, or sham. Following stimulation, all participants completed a spatial cueing task involving both gaze and arrow cues. Two stimulus onset asynchrony (SOA) conditions (200 ms and 600 ms) were implemented to investigate how timing modulates the processing of these cues within the rOFC.

Interventions

BEHAVIORALGaze cues

use eye gaze images as cues

BEHAVIORALArrow cues

use arrow images as cues

BEHAVIORALSOA 200 ms

The stimulus onset asynchrony (SOA) between the cue and the target was 200 ms.

BEHAVIORALSOA 600 ms

The stimulus onset asynchrony (SOA) between the cue and the target was 600 ms.

BEHAVIORALCongruent

The cue is spatially congruent with the target.

BEHAVIORALIncongruent

The cue is spatially incongruent with the target.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

* history of head injury * no implants in the head * medical or psychiatric illness.

Design outcomes

Primary

Measure	Time frame	Description
Reaction time to the judgment of the target location.	1 hour	The primary analysis focused on the reaction times for judging the target location under each condition.

Secondary

Measure	Time frame	Description
Magnitude of the cueing effect	1 hour	This index is derived by subtracting the congruent reaction time from the incongruent reaction time to quantify the magnitude of the cueing effect.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 19, 2026