Advanced Primary Open Angle Glaucoma, Intraocular Pressure, Subthreshold Diode Laser, Trabeculotomy
Conditions
Brief summary
This study aimed to compare between subthreshold diode laser and trabeculotomy in treatment of advanced primary open angle glaucoma throughout 12 months follow-up.
Detailed description
Glaucoma is a common eye disease that can cause irreversible blindness if left undiagnosed and untreated. Glaucoma is caused by elevated intraocular pressure (IOP) that leads to optic nerve damage and visual field loss. Trabeculectomy operation was first described more than 50 years ago and is considered the most commonly performed surgery worldwide for glaucoma patients. Subthreshold transscleral cyclophotocoagulation is a micropulse delivery mode of diode laser that has been used recently to treat glaucoma by ablating the ciliary processes and reducing the aqueous humour production.
Interventions
PROCEDURESubthreshold diode laser
Patients scheduled for subthreshold diode laser.
PROCEDURETrabeculotomy
Patients scheduled for trabeculotomy.
Sponsors
Kafrelsheikh University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients older than 18 years. * Open angle glaucoma. * Advanced glaucoma (visual field deterioration MD\>-12.00 dB with evidence of optic neuropathy despite maximal therapy).
Exclusion criteria
* Previous intraocular surgery for glaucoma. * Patients who had undergone previous laser therapy for glaucoma. * Cases of secondary glaucoma. * Media opacity interferes with capturing fundus image.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity | 12 months postoperatively | Visual acuity was evaluated using finger counting, hand motion, or light perception |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure | 12 months postoperatively | Intraocular pressure was measured and success criteria included an IOP ranging from 6 to 21 mmHg or a minimum 20% decline from baseline, with or without antiglaucoma drugs. |
| Degree of pain | 12 months postoperatively | Postoperative pain was assessed using a visual analogue scale from 0 to 10 cm: 0-4 cm for mild, 5-7 cm for moderate, and 8-10 cm for intense pain. |
Countries
Egypt
Outcome results
None listed