Metabolic Syndrome, Obesity & Overweight
Conditions
Keywords
Korean ginseng extract, Ginseng supplementation, Fatigue, Body composition
Brief summary
This study evaluated whether eight weeks of Korean ginseng extract supplementation could affect exercise performance, body composition, and selected blood-based physiological markers in healthy adults. A total of 60 healthy adults aged 20 to 50 years were recruited and randomly assigned to either a Korean ginseng extract group or a placebo group in a double-blind, placebo-controlled design. Participants consumed one 10 mL packet of Korean ginseng extract or placebo daily for eight weeks. Assessments were performed before and after the intervention. Outcome measures included exercise performance tests, body composition, endocrine markers, inflammatory markers, oxidative stress markers, immune cell indices, and blood cell counts. Forty-nine participants completed the post-intervention assessments. The study was approved by the University of Taipei Institutional Review Board under approval number IRB-2023-011.
Interventions
DIETARY_SUPPLEMENTKorean Ginseng Extract
Korean ginseng extract supplement, provided as one 10 mL packet daily for eight weeks. The supplement contained ginseng extract, water, and fructooligosaccharides.
OTHERPlacebo
Placebo supplement, provided as one 10 mL packet daily for eight weeks. The placebo was designed to have a similar taste and appearance to the Korean ginseng extract supplement and contained water, maltodextrin, fructooligosaccharides, and casein phosphopeptide.
Sponsors
University of Taipei
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Masking description
Participants and investigators were masked to group assignment. The placebo was designed to have a similar taste and appearance to the Korean ginseng extract supplement.
Intervention model description
Participants were randomly assigned in a 1:1 ratio to receive either Korean ginseng extract or placebo once daily for eight weeks.
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged 20 to 50 years. * Able and willing to participate in the study. * Able to provide written informed consent.
Exclusion criteria
* Allergy to ginseng products. * History of cardiovascular disease, asthma, diabetes, liver disease, kidney disease, arrhythmia, or other chronic diseases. * Current use of medications for chronic diseases. * Habitual use of ginseng or other traditional Chinese medicine-related supplements. * Pregnancy or breastfeeding. * Menopausal women.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Biceps Strength | Baseline and 8 weeks | Change in biceps isokinetic strength from baseline to after eight weeks of supplementation, assessed using an isokinetic dynamometer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in VO2max | Baseline and 8 weeks | Change in maximal oxygen uptake from baseline to after eight weeks of supplementation, assessed using a cycle ergometer and portable gas analysis system. |
Countries
Taiwan
Outcome results
None listed