Evaluation of Low Energy Level Laser Biostimulation at Different Energy Densities in the Treatment of Temporomandibular Joint Irregularities: A Retrospective Study

The Study Was Conducted by Retrospectively Analysing the Files of Patients Who Presented With Temporomandibular Joint Disorder (TMD) and Underwent LLEL Treatment. Patients Were Divided Into Myalgia, Disc Displacement With Reduction and Follow-up Groups. In Our Study, GaAl-As Diode Laser (EzLase 940, Biolase Technology, Inc. 4 Cromwell Irvine, USA) for Lowlevel Laser Treatment Was Applied for 1 Minute to Subgroup 1 (940 nm, 1. 5 W, 90 J, Continuous), Subgroup 2 (940 nm, 3 W, 180J, Continuous) and Subgroup 1 (940 nm, 1.5 W, 90J, Continuous) and Subgroup 2 (940 nm, 3 W, 180J, Continuous).

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07588841

Enrollment

100

Registered

2026-05-15

Start date

2022-09-03

Completion date

2024-12-24

Last updated

2026-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myalgia of Mastication Muscle

Brief summary

This clinical study aimed to evaluate the effectiveness of low-level laser therapy in patients with temporomandibular disorders (TMD), specifically disc displacement with reduction and myalgia. The study compared laser therapy with a soft diet approach to determine whether laser treatment provides additional benefits in reducing pain and improving jaw function

Interventions

OTHERLow Level Laser Therapy

Participants received low-level laser therapy applied to the temporomandibular joint region in addition to soft diet recommendations. Treatment was performed in 9 sessions according to the predefined laser protocol. Participants followed a soft diet regimen without receiving laser therapy and served as the comparison group.

OTHERDietary Supplement

Participants in this group did not receive laser therapy and were instructed to follow a soft diet during the study period. This group served as the comparison group for evaluating treatment outcomes.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

Participants were assigned to one of two parallel groups: a low-level laser therapy group or a soft diet group. Outcomes were assessed at baseline, after completion of treatment sessions, and during follow-up evaluations.

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Inclusion criteria

Diagnosis of disc displacement with reduction (DDwR) and myalgia according to DC/TMD criteria Presence of temporomandibular joint pain and functional limitation Patients aged 18 years and older No previous temporomandibular joint (TMJ) treatment Absence of systemic diseases Willingness to participate and provide informed consent

Exclusion criteria

History of previous TMJ treatment (e.g., conservative or surgical treatment) Congenital or inflammatory joint disease Severe systemic diseases Edentulous patients Children and adolescents in the active growth period Acute trauma history involving the TMJ region Inability or unwillingness to complete follow-up visits

Design outcomes

Primary

Measure	Time frame	Description
Change in temporomandibular pain intensity measured by the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up	6 month	Change in temporomandibular pain intensity was assessed using the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up. The Visual Analog Scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Higher scores represent greater pain severity.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 16, 2026