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Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.

Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07587190
Enrollment
280
Registered
2026-05-14
Start date
2025-09-01
Completion date
2028-12-31
Last updated
2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Practice Guidelines for Primary Care of Acute Abdomen

Keywords

Acute Abdomen, Practice guidelines, Primary Health Care, Adaptation, Implementation Strategies, Effectiveness-Implementation Hybrid Type 2 Study Design

Brief summary

The study aims 1) to adapt, 2) to develop implementation strategies for and 3) to evaluate the effect of implementing a practice guideline for acute abdomen at primary care level in Zambia. We employ a sequential exploratory mixed method study design. Qualitative and quantitative data from health care workers will be used to adapt a practice guideline developed in a high-income into a low- and middle-income (LMIC) context and to develop strategies for successful implementation. The primary outcome of interest is the prospective change in length of stay in hospital among patients presenting with acute abdomen in the intervention site compared to the control site. The study will address the scarcity of literature on practice guidelines for acute abdomen in the LMIC context. The implementation of an adapted guideline may contribute to a reduction of the morbidity and mortality rates associated with acute abdomen in this setting by increasing management capacity at the primary care level.

Interventions

OTHERPractice guidelines for primary care of acute abdomen

Adjusted practice guidelines for primary care of acute abdomen will be implemented at the intervention site.

OTHERNo intervention

The control site will receive no intervention.

Sponsors

University of Bergen
Lead SponsorOTHER
University of Zambia
CollaboratorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Data from all patients 18 year and older with acute abdomen including surgical, gynecological and medical acute abdomen managed at the intervention site and control site will be collected during the study period.

Exclusion criteria

* All cases of acute abdomen secondary to trauma will be excluded from the study. All patients in the immediate postoperative phase operated from other facilities presenting with acute abdomen.

Design outcomes

Primary

MeasureTime frameDescription
Length of Hospital Stay7 daysThe duration of time in days that a patient with acute abdomen stays in the hospital from the day of admission to discharge

Countries

Zambia

Contacts

CONTACTWilson Mbewe, MD
wimbe8573@uib.no+260977466316
STUDY_DIRECTORElisabeth Marie Strømme, MD, PhD

University of Bergen

STUDY_DIRECTORThomas Mildestvedt, MD, PhD

University of Bergen

STUDY_DIRECTOREivind Meland

University of Bergen

STUDY_DIRECTORMpundu Makasa

University of Zambia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026