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Step-Up vs. Running Exercise at Matched Heart Rate Zones in Sedentary Males

Assessment of Cardiovascular, Autonomic, and Isometric Leg Strength Adaptations Following Step-Up Versus Running Exercise at Matched Heart Rate Zones in Sedentary Males

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07585617
Enrollment
36
Registered
2026-05-14
Start date
2024-02-20
Completion date
2024-06-10
Last updated
2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical Inactivity, Sedentary Behaviors

Keywords

Exercise intervention, Heart rate variability, VO2max, Isometric strength, Step-up exercise, Aerobic training

Brief summary

This study compares the effects of two aerobic exercise methods - loaded step-up exercise and treadmill running - on cardiovascular fitness, leg strength, heart rate variability, and recovery in sedentary adult males. Both exercise groups will train at 80-85% of maximum heart rate, three sessions per week for six weeks. A control group will not participate in any training. Measurements of estimated VO₂max, isometric leg strength, resting heart rate, heart rate variability indices, and heart rate recovery will be taken before and after the intervention.

Interventions

BEHAVIORALLoaded Step-Up Exercise

Step-up exercise performed on an adjustable platform at individually assigned heights (35 cm or 40 cm, based on participant height), with a load equal to 20% of body weight, at 80-85% of maximum heart rate, 3 sessions per week for 6 weeks with progressive volume increase.

Continuous treadmill running at 80-85% of maximum heart rate, 3 sessions per week for 6 weeks with progressive volume increase.

Sponsors

Ankara University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Male, aged 18-40 years * Sedentary - no participation in structured exercise programs for at least 6 months prior to the study * Free from chronic diseases * No musculoskeletal injuries or surgical interventions within the last 6 months

Exclusion criteria

* Female sex * Age below 18 or above 40 years * Participation in structured exercise within the last 6 months * Presence of chronic disease * Musculoskeletal injury or surgical intervention within the last 6 months

Design outcomes

Primary

MeasureTime frameDescription
Estimated VO2maxBaseline and 6 weeksEstimated maximal oxygen uptake assessed via Yo-Yo Intermittent Recovery Test Level 1
Isometric Leg StrengthBaseline and 6 weeksMaximum isometric leg strength measured using a Takei back-leg lift dynamometer

Secondary

MeasureTime frameDescription
Heart Rate VariabilityBaseline and 6 weeksHRV indices including pNN50 and MeanRR measured via Polar H10 during supine rest
Heart Rate RecoveryWeeks 1 through 6Time to recovery after and between sets of exercise sessions measured weekly across the 6-week intervention

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026