Pharmacokinetics of Essential Oils in Different Capsules

Inclusion criteria

Selection Criteria: Participants must meet all the following criteria: * Adults ages 18-35 years old * Local to metropolitan Jackson, MS, and/or willing to come to the clinical research center for study visits * Willing to wash out of all internally consumed essential oil and botanical products for at least 2 weeks prior to starting the study and willing to maintain the washout for the duration of the study (approximately 8 weeks) * Willing to avoid all frankincense, wild orange, and lemon essential oil in any form (aromatic, topical, or internal) for the duration of the study (approximately 5 weeks). * Willing to avoid alcohol, recreational drugs, and smoking/vaping for 3 days prior to each arm of the study * Willing to receive an intravenous catheter in the arm or hand every two weeks for 4 weeks (three times total) * History of successful blood/plasma donation, IV insertion, or blood collection by phlebotomy * Weigh at least 110 pounds * No uncontrolled metabolic disease * No unstable major diseases under treatment by healthcare professional * No pregnancy within the last 60 days or currently breastfeeding (females) * No allergy to olive oil or frankincense, lemon, or wild orange essential oils * No regular internal consumption of frankincense, lemon, or wild orange essential oil regularly within the last 1 month (regularly is defined as dosing daily for more than 2 consecutive weeks, or dosing more than 2-3 times per week for 4 consecutive weeks) * No alcohol, recreational drug, or smoking/vaping use in the past 3 days * No evidence of medical condition, significant disease or disorder, medication, or surgery within the past 12 months that may, in the judgment of the medical provider, put the participant at risk or affect study results, procedures, or outcomes * Not currently or previously participating in any other clinical trial within the last 30 calendar days