Exercise Performance Impairment, Menstrual Cycle
Conditions
Keywords
Eccentric exercise, Exercise induced muscle damage
Brief summary
The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited. The protective role of estrogens against muscle microdamage is supported by findings from some studies; however, it is questioned by others. The aim of the present study was to investigate the effect of eccentric exercise on biomarkers of muscle microdamage and on oxygen uptake during two phases of the menstrual cycle in healthy premenopausal women.
Interventions
OTHERIsokinetic eccentric exercise using knee extensors of the right lower limb
Isokinetic eccentric exercise consisted of 10 min at 40% of maximal voluntary contractions, followed by 2 min maximal intensity muscle effort
OTHERIsokinetic eccentric exercise using knee extensors of the left lower limb
Isokinetic eccentric exercise consisted of 10 min at 40% of maximal voluntary contractions, followed by 2 min maximal intensity muscle effort
Sponsors
National and Kapodistrian University of Athens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 28 Years
Healthy volunteers
Yes
Inclusion criteria
* No known medical history * Not receiving any medication or dietary supplementation. * Stable menstrual cycle
Exclusion criteria
* Pathological conditions the last month before enrolment in the study * Low limb injury the past 4 months * Unstable menstrual cycle
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal isometric torque | From enrollment to the end of the intervention at 2 weeks | maximal performance during 5 sec isometric knee extensors contraction, assessed pre and 48 h post eccentric exercise |
| Delayed onset muscle soreness | From enrollment to the end of intervention at 2 weeks | Palpation of the muscle belly, performed pre and 48h post eccentric exercise |
| Oxygen consumption | From enrollment to the end of the intervention at 2 weeks | During the isokinetic eccentric exercise, participants were attached to a gas analyser for continuously measuring oxygen consumption. |
| Duration of the isokinetic exercise | From enrollment to the end of intervention at 2 weeks | The total duration of exercise performed on the isokinetic dynamometer was recorded |
Countries
Greece
Contacts
PRINCIPAL_INVESTIGATORVassilis Paschalis, PhD
National and Kapodistrian University of Athens
Outcome results
None listed