Skip to content

A Study Of Starting Strength Barbell Training

Effects Of Progressive Barbell Strength Training On Cardiovascular And Metabolic Health Markers

Status
Suspended
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07578285
Enrollment
200
Registered
2026-05-11
Start date
2027-07-01
Completion date
2029-01-01
Last updated
2026-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Pressure, Fasting Glucose, Lipid Profile

Brief summary

The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure.

Interventions

OTHERProgressive Barbell Strength Training

Subjects will participate in a 12-week barbell training program, 3 days per week for approximately 60 minutes each session. Training sessions will be conducted by Starting Strength certified coaches at Starting Strength Scottsdale gym. Core barbell movements including but not limited to: squat, deadlift, bench press, overhead press, and power clean.

Sponsors

Mayo Clinic
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
15 Years to 100 Years
Healthy volunteers
Yes

Inclusion criteria

* Adults aged 18-100 years * Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week) * No participation in structured resistance training programs within the past 6 months. * Able to safely participate in resistance training as determined by medical screening * Willing to commit to 3 training sessions per week for 12 weeks * Able to provide informed consent * Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company.

Exclusion criteria

* Current participation in structured resistance training programs * Cardiovascular disease requiring activity restriction * Uncontrolled hypertension (systolic BP \>180 mm Hg or diastolic BP \>110 mm Hg) * Musculoskeletal conditions precluding safe barbell training * Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment * Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training

Design outcomes

Primary

MeasureTime frameDescription
Change in systolic blood pressureBaseline, 16 weeksBlood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
Change in diastolic blood pressureBaseline, 16 weeksBlood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)

Secondary

MeasureTime frameDescription
Change in total cholesterolBaseline, 16 weeksTotal cholesterol is the sum of a person's HDL cholesterol, LDL cholesterol, and 20% of their triglyceride levels. Healthy total cholesterol is less than 200 mg/dL of blood
Change in low-density lipoprotein cholesterol (LDL-C)Baseline, 16 weeksLow-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 100 mg/DL and below are considered healthier.
Change in high-density lipoprotein cholesterol (HDL-C)Baseline, 16 weeksHigh-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 60 mg/DL and above are considered healthier.
Change in triglyceridesBaseline, 16 weeksTriglycerides are measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 150 mg/DL and below are considered normal levels.
Change in fasting glucoseBaseline, 16 weeksBlood sample taken after an overnight fast. Reported in millimoles per liter (mmol/l)

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORJoshua Lee, PA-C,MPAS

Mayo Clinic

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 15, 2026