Burn Injury, Pulmonary Rehabilitation
Conditions
Keywords
Upper Extremity Burns, Pulmonary Rehabilitation, Respiratory Function
Brief summary
This study will evaluate the effects of a pulmonary rehabilitation program on breathing function, respiratory muscle activity, respiratory muscle thickness, and functional capacity in adults with upper extremity burns. Participants will be randomly assigned to either a pulmonary rehabilitation group or a control group. The pulmonary rehabilitation group will receive respiratory muscle training together with upper extremity aerobic exercises, while the control group will receive a conventional exercise program. Assessments will be performed before the intervention, at week 3, and after the 6-week intervention period. The results may help improve rehabilitation approaches for people with upper extremity burns.
Detailed description
Burn injuries may lead to physical limitations, functional loss, and respiratory problems. In individuals with upper extremity burns, pain, scar tissue, and reduced mobility of the shoulder girdle and chest wall may affect breathing mechanics and respiratory muscle performance. These changes may reduce ventilatory capacity and functional capacity during daily activities. This randomized controlled clinical study will investigate the effects of a pulmonary rehabilitation program in adults with upper extremity burns. The study will be conducted at the Burn Center of Kartal Dr. Lütfi Kırdar City Hospital. Adults aged 18 to 65 years who had an upper extremity burn injury 3 to 12 months before enrollment and who meet the eligibility criteria will be included. A total of 64 participants will be randomly assigned to two groups: a pulmonary rehabilitation group and a control group. The pulmonary rehabilitation group will receive respiratory muscle training combined with upper extremity aerobic exercises. The control group will receive a conventional exercise program. The intervention period will last 6 weeks. Participants will be assessed at three time points: before the intervention, at week 3, and after the 6-week intervention. Respiratory function will be assessed using spirometry, including forced vital capacity, forced expiratory volume in one second, and maximum voluntary ventilation. Respiratory muscle activity will be evaluated using surface electromyography. Respiratory muscle thickness and diaphragm excursion will be assessed using ultrasonography. Functional capacity will be measured with the 6-minute walk test. The study aims to determine whether pulmonary rehabilitation can improve respiratory function, respiratory muscle activity, respiratory muscle morphology, and functional capacity in individuals with upper extremity burns.
Interventions
Participants in the experimental group will receive a 6-week pulmonary rehabilitation program in addition to the conventional exercise program. The pulmonary rehabilitation program will include respiratory muscle training and upper extremity aerobic exercises. Respiratory muscle training will be performed to improve inspiratory and expiratory muscle performance. Upper extremity aerobic exercises will be planned according to the participant's clinical status and tolerance, with the aim of improving respiratory function, chest wall mobility, exercise tolerance, and functional capacity. Exercises will be progressed gradually during the intervention period, and participants will be monitored for dyspnea, fatigue, oxygen desaturation, and pain during the sessions.
Participants in both groups will receive a 6-week conventional exercise program as standard rehabilitation. The program will include routine rehabilitation exercises commonly used for individuals with upper extremity burns. Exercises will focus on maintaining and improving upper extremity range of motion, flexibility, scar-related mobility, posture, and functional use of the affected limb. The program may include active and active-assisted range of motion exercises, stretching exercises, mobility exercises for the shoulder, elbow, wrist, and hand, and functional upper extremity activities according to the participant's clinical condition and tolerance.
Sponsors
Fenerbahce University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
The outcome assessor will be blinded to group allocation. Participants will be randomly assigned to the pulmonary rehabilitation group or the control group, and outcome measurements will be performed by an assessor who is not involved in the intervention program and is unaware of the participants' group assignments.
Intervention model description
Participants will be randomly assigned to one of two parallel groups. The experimental group will receive pulmonary rehabilitation, including respiratory muscle training and upper extremity aerobic exercises. The control group will receive a conventional exercise program. Both groups will be assessed at baseline, week 3, and week 6.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Adults aged 18 to 65 years * History of upper extremity burn injury 3 to 12 months before enrollment * Clinically stable condition, including oxygen saturation greater than 92% and cardiac stability * Ability to communicate and follow instructions, with no hearing, cognitive, or motor communication impairment * Voluntary agreement to participate in the study and signing the informed consent form
Exclusion criteria
* Burns involving the lower extremity, trunk, or head and neck regions * History of chronic pulmonary, cardiac, neurological, or musculoskeletal disease * Dependence on mechanical ventilation or respiratory support * Severe psychiatric disorder or cognitive impairment * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Forced Vital Capacity | Baseline, week 3, and week 6 | Pulmonary function will be assessed using forced vital capacity measured with a portable spirometry device according to American Thoracic Society and European Respiratory Society standards. Forced vital capacity will be reported in liters. |
| Change in Forced Expiratory Volume in One Second | Baseline, week 3, and week 6 | Pulmonary function will be assessed using forced expiratory volume in one second measured with a portable spirometry device according to American Thoracic Society and European Respiratory Society standards. Forced expiratory volume in one second will be reported in liters. |
| Change in Maximum Voluntary Ventilation | Baseline, week 3, and week 6 | Pulmonary function will be assessed using maximum voluntary ventilation measured with a portable spirometry device according to American Thoracic Society and European Respiratory Society standards. Maximum voluntary ventilation will be reported in liters per minute. |
| Change in Diaphragm Thickness During Inspiration | Baseline, week 3, and week 6 | Diaphragm thickness during inspiration will be assessed using ultrasonography to evaluate changes in diaphragm morphology over time. Diaphragm thickness during inspiration will be reported in millimeters. |
| Change in Diaphragm Thickness During Expiration | Baseline, week 3, and week 6 | Diaphragm thickness during expiration will be assessed using ultrasonography to evaluate changes in diaphragm morphology over time. Diaphragm thickness during expiration will be reported in millimeters. |
| Change in Diaphragm Excursion | Baseline, week 3, and week 6 | Diaphragm excursion will be assessed using ultrasonography to evaluate changes in diaphragm mobility over time. Diaphragm excursion will be reported in millimeters. |
| Change in 6-Minute Walk Distance | Baseline, week 3, and week 6 | Functional capacity will be assessed using the 6-minute walk test. The distance walked during the test will be recorded in meters. |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORSümeyye Akçay
Fenerbahçe University
Outcome results
None listed