Peer Support Intervention for Caregivers of Patients Undergoing HSCT

Peer Support Intervention for Caregivers of Patients Undergoing Hematopoietic Stem Cell Transplantation: Feasibility and Preliminary Efficacy Trial

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07577674

Acronym

STEPP-Care

Enrollment

Registered

2026-05-11

Start date

2026-09-30

Completion date

2031-09-30

Last updated

2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematopoietic Stem Cell Transplantation

Keywords

Caregivers, Stem Cell Transplantation

Brief summary

The main purpose of this study is to determine if a tailored peer support intervention (STEPP-Care) is feasible among caregivers of patients undergoing hematopoietic stem cell transplantation (HSCT).

Detailed description

Caregivers play a vital role in recovery following hematopoietic stem cell transplantation (HSCT). However, caregiving can contribute to psychological distress and reduced quality of life (QOL). Additionally, HSCT caregivers report low self-efficacy and social support, protective factors which would otherwise help bolster their confidence in coping with the uncertainties and challenges of HSCT. Given the challenges and unmet psychosocial needs of HSCT caregivers, peer support interventions are poised to promote caregiver coping to address caregiver distress and quality of life concerns. With limited tailored peer support interventions, for HSCT caregivers, this study aims to assess the feasibility and acceptability of a peer support intervention (STEPP-Care) and examine its preliminary effects for improving QOL, caregiver burden, and psychological well-being compared to usual care in 90 caregivers of HSCT recipients.

Interventions

BEHAVIORALSTEPP-Care

STEPP-Care is a phone-delivered six-session structured peer support intervention for caregivers of patients undergoing hematopoietic stem cell transplantation.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult caregivers (≥18 years of age) of patients with hematologic malignancies who are undergoing autologous or allogeneic HSCT at Dana-Farber Cancer Institute. * Is a relative or friend who is identified by the patient to be their caregiver. * Ability to speak, read, and respond in English * Has access to a phone.

Exclusion criteria

* Caregivers with acute or unstable psychiatric conditions or other cognitive conditions that the treating oncologist believes would prohibit informed consent or ability to adhere to study procedures.

Design outcomes

Primary

Measure	Time frame	Description
Intervention Feasibility	up to 10 weeks	Feasibility can be defined as \>/= 60% of STEPP-Care recipients completing 4/6 sessions
Intervention Acceptability	up to 10 weeks	Acceptability can be defined as average STEPP-Care intervention participant ratings \>20 on the Client Satisfaction Questionnaire

Contacts

CONTACTHermioni L. Amonoo, MD, MPP, MPH

hermioni_amonoo@dfci.harvard.edu617-525-7472

CONTACTJosephine Monahan, BA

jamonahan@bwh.harvard.edu

PRINCIPAL_INVESTIGATORHermioni L. Amonoo, MD, MPP, MPH

Brigham and Women's Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 12, 2026