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Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases

Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07574931
Enrollment
40
Registered
2026-05-08
Start date
2024-04-16
Completion date
2026-02-28
Last updated
2026-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ablation of Arrhythmias, Arrhythmia, Congenital Heart Disease

Keywords

Congenital heart disease, Catheter ablation, arrhythmia, Radiofrequency, 3D Mapping, tachycardia., Outcome

Brief summary

Our observational study aim to to evaluate the incidence of Tachyarrhythmia in patients with congenital heart diseases (corrected/non corrected) and the effectiveness of catheter ablation.RF catheter ablation was performed to all patients and follow up for recurrence was done for one year.

Detailed description

This is a prospective cohort observational study including patients with CHD undergoing attempted catheter ablation.Baseline information is collected before catheter ablation. Data include demographic characteristics (age, gender), type of CHD, dates and types of previous cardiac surgeries, comorbidities, Electrocardiographic (ECG) and ECG recordings Holter (24h to 7 days) during tachycardia to document arrhythmia type and the presence of resting pre-excitation, palpitations attacks (frequency, duration, ICU / ER admission, ECG and mode of termination), history of supraventricular and ventricular arrhythmias, pharmacological therapy, previous catheter ablation and cardiac imaging (echocardiography with or without cardiac magnetic resonance imaging or cardiac computed tomography). RF catheter ablation is performed after obtaining informed consent from all patients. Antiarrhythmic medication is in most cases discontinued for at least five half-lives before the procedure. Prepping and draping are performed according to standard hospital protocols under complete local aseptic conditions. Variable sized sheaths are introduced percutaneously via the right/left femoral/Jugular/ subclavian vein. Under fluoroscopic guidance, three electrode catheters are positioned as follows: at the high right atrium, from the His bundle region to the right ventricle, and in the coronary sinus (CS) ostium region. Bipolar intracardiac electro grams filtered between 30 and 500 Hz along with the 12- lead surface ECG were simultaneously recorded and stored digitally on a computerized multichannel EP recording system. Cases are filtered according to complexity and availability of 3D to conventional group for simple cases where RF ablation will be done guided by Conventional fluoroscopic guidance and for complicated cases RF ablation is guided by 3d electro anatomical mapping system.

Interventions

None listed

Sponsors

Fayoum University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with congenital heart diseases (corrected / non corrected) with documented arrhythmia * Patients with congenital heart diseases without documented arrhythmia but frequent palpitations.

Exclusion criteria

* Pregnant * Patients with unstable hemodynamics * End stage diseases e.g.: cancer stage IV

Design outcomes

Primary

MeasureTime frameDescription
the rate of acute success of catheter ablationFrom timing of catheter ablation till about one hourdefined as termination of the clinical arrhythmia with non-inducibility of this clinical arrhythmia during Catheter ablation
rate of recurrence of tachyarrhythmias after catheter ablationone year

Secondary

MeasureTime frame
The types of Tachyarrhythmia in patients with congenital heart diseasesOne year

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 9, 2026