Periodontal Disease, Periodontal Diseases, Periodontitis
Conditions
Keywords
Candida Albicans, Candida, Periodontitis, Sabouraud Dextrose Agar, Culture
Brief summary
Periodontitis is a significant oral health issue characterized by inflammation and destruction of the supporting structures of the teeth. Recent research has indicated that Candida albicans, a common fungal pathogen, may play a role in the exacerbation of periodontal diseases. This study aims to investigate the prevalence and impact of Candida albicans in Syrian patients diagnosed with periodontitis, contributing to a better understanding of its role in oral health within this population.
Interventions
DIAGNOSTIC_TESTPeriodontal Assessment and Sample Collection from Subgingival Pockets
Clinical examination to assess periodontal status. Collection of subgingival plaque samples for microbiological analysis to identify Candida Albicans.
Sponsors
Al-Hawash Private University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients aged 18 years and older. * Diagnosed with chronic periodontitis based on clinical examination (attachment loss, probing depth). * Consent to participate in the study.
Exclusion criteria
* Patients with systemic diseases affecting oral health (e.g., diabetes, immunosuppressive conditions). * Recent antibiotic or antifungal treatment within the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of Candida Species in Subgingival Samples | At enrollment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Periodontal Screening and Recording Index | At enrollment | Periodontal parameters are measured using the WHO probe by dividing the mouth into six sextants (three upper, three lower). The highest score in each sextant is recorded. Scoring from 0-4 is based on pocket depth, gingival health, and calculus presence. Scoring Criteria: 0: Healthy periodontium, black band visible. 1. Bleeding on probing (BOP), black band visible. 2. Calculus present, black band visible. 3. Pocket depth 3.5-5.5 mm (black band partially submerged). 4. Pocket depth \> 5.5 mm (black band entirely hidden). |
Countries
Syria
Contacts
CONTACTAli Abou Sulaiman
PRINCIPAL_INVESTIGATORAli Abou Sulaiman, Ph.D. in Periodontology
Al-Hawash Private University
Outcome results
None listed