Postoperative Pain Following Root Canal Treatment With Bioceramic Sealers

Postoperative Pain and Sealer Extrusion Following Root Canal Treatment With Neosealer Flo and Ceraseal Bioceramic Sealers; a Randomized Clinical Trial

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07574801

Enrollment

Registered

2026-05-08

Start date

2026-05-01

Completion date

2026-09-08

Last updated

2026-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible Acute Pulpitis, Root Canal Treatment

Keywords

postoperative pain, bioceramic sealer, extrusion, root canal treatment

Brief summary

To evaluate and compare postoperative pain and extrusion of sealers following root canal treatment using NeoSealer Flo and CeraSeal bioceramic sealers

Interventions

PROCEDUREroot canal treatment

nanosealer flo bioceramic root canal sealer

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

1. Molar teeth requiring root canal treatment 2. Diagnosed with symptomatic irreversible pulpitis, 3. Patients able to understand and use the VAS scale

Exclusion criteria

1. Patients with systemic diseases affecting pain perception 2. Use of analgesics within 12 hours before treatment 3. Previously treated teeth 4. Teeth with periapical abscess or swelling

Design outcomes

Primary

Measure	Time frame	Description
postoperative pain	24 and 48 hours	postoperative pain will be measured using a visual analogue scale ( after being introduced and discussed with the patient) at 2 time points, pain will be categorized as no pain, moderate and severe.

Secondary

Measure	Time frame	Description
sealer extrusion	immediate postoperatively	sealer extrusion will be measured radiographically using standardized digital periapical posttreatment radiographs via a blinded examiner and recorded as binary outcome: present/ absent.

Contacts

CONTACTSara Gamal Elgamal

sara.elgamal@dentistry.cu.edu.eg00201094557105

CONTACTHeba ibrahim Mohammady

heba.mohamdy@dentistry.cu.edu.eg

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 9, 2026