Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function

Comparative Examination of Ulnar and Median Nerve Electromyography Examinations to Monitor Intraoperative Neuromuscular Function

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07571395

Enrollment

Registered

2026-05-06

Start date

2026-06-16

Completion date

2028-03-31

Last updated

2026-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective Surgery, Nerve Conduction Study, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery

Keywords

electromyography, neuromuscular blockade monitoring, median nerve

Brief summary

The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.

Interventions

DIAGNOSTIC_TESTElectromyography

Electromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA I-III physical status * elective surgery requiring muscle relaxation * both arms are available during surgery in the same position for neuromuscular blockade monitoring * signed informed consent form

Exclusion criteria

* neruomuscular disorder in patient history (eg. stroke, myasthenia) * innervation problem in either arms (eg. carpal tunnel syndrome) * deformity to either arms (eg. Dupyurten contracture, severe arthritis) * Severe hepatic or renal insufficiency that affects muscle relaxant pharmacokinetics * skin lesions at the site of electrode placement * implanted pacemaker jelenléte * gravidity * muscle relaxant needs to be repeated during surgery

Design outcomes

Primary

Measure	Time frame	Description
CMAP	Baseline	Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar

Secondary

Measure	Time frame	Description
Recovery time	Perioperative	Time from muscle relaxant administration to spontaneous recovery to TOFR\>0,9 monitored with median and ulnar nerve stimulation
Onset time	Baseline	Time from administration of muscle relaxant to disappearance of twitch response (TOFC0) monitored with median and ulnar nerve stimulation

Countries

Hungary

Contacts

CONTACTReka Nemes, MD PhD

nemes.reka@med.unideb.hu+36 30 966 8722

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 18, 2026