Lichen Planus
Conditions
Keywords
Lichen Planus, Taste Function, Smell Function, Olfactory Testing, Gustatory Testing, Nasal Endoscopy, Oral Mucosa, Nasal Mucosa, Mucosal Involvement, Healthy Controls
Brief summary
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes. Adults aged 18-65 with lichen planus participated in taste and smell tests. Oral and nasal examinations were performed to check for mucosal involvement, and nasal endoscopy was used to further evaluate nasal involvement. A healthy control group of similar age also underwent taste and smell tests to compare results with the lichen planus patients. The study aims to better understand how lichen planus affects smell and taste, which may help improve patient care. Participation is voluntary, and all information collected will be kept confidential.
Detailed description
The study aims to evaluate the impact of lichen planus on olfactory and gustatory functions in adults aged 18-65. Participants with lichen planus underwent taste and smell testing, oral and nasal mucosal examinations, and nasal endoscopy to detect potential mucosal involvement. A matched healthy control group also completed taste and smell tests to provide comparative data. This design allows the assessment of whether mucosal involvement in lichen planus correlates with changes in taste and smell, which may contribute to better clinical understanding and management of the disease.
Interventions
OTHERGrup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
Group 1 - Lichen Planus Patients: Participants undergo taste and smell testing to assess sensory function, oral and nasal examinations to evaluate mucosal involvement, and nasal endoscopy for detailed nasal assessment. Group 2 - Healthy Controls: Participants undergo taste and smell testing to provide comparative data for the lichen planus group.
Sponsors
Istanbul Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
Age 18-65 years Clinically diagnosed with lichen planus (patient group) Healthy individuals without lichen planus (control group) Willing and able to provide informed consent
Exclusion criteria
Nasal septum deviation Nasal polyposis, congenital olfactory dysfunction, chronic rhinosinusitis, or allergic rhinitis History of head trauma History of nasal or paranasal surgery Psychiatric or neurological disorders (e.g., Parkinson's disease, Alzheimer's disease) Persistent loss of smell following COVID-19 infection Pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Smell and Taste Function | Day 1 | Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. Time Frame: Single visit assessment |
| Smell and taste function in patients with lichen planus | Day 1 | Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORYasemin Bolat Eren, MD
S.B.U. Istanbul Eğitim ve Araştırma Hastanesi, Dermatology Department
Outcome results
None listed