Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations

Evaluation of Dentoalveolar Changes Following Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations in Deep Bite Cases: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07566676

Acronym

MOPs

Enrollment

Registered

2026-05-05

Start date

2026-05-01

Completion date

2029-06-01

Last updated

2026-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Bite Malocclusion, Intrusion of Tooth, Orthodontic Tooth Movement, Root Resorption

Brief summary

Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.

Detailed description

Micro-osteoperforations (MOPs) are a new, simple, and minimally invasive technique to accelerate tooth movement. The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increased bone resorption, the catabolic phase of tooth movement, in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement and decrease root resotption.

Interventions

PROCEDUREMicro-osteoperforations

Using utility arch with micro-osteoperforations (MOPs). The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increase bone resorption and the catabolic phase of tooth movement in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement at the apices above maxillary incisors to evaluate the amount of movement and amount of root resorption.

DEVICEUtility arch

Patients will receive utility arch for intrusion of maxillary incisors without micro-osteoperforations.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

15 Years to 25 Years

Healthy volunteers

Inclusion criteria

1. Patients age between 15-25 years. 2. Patients with overbite ≥ 4 mm. 3. All permanent teeth erupted (excluding 3rd molars). 4. No previous orthodontic treatment. 5. Patients with good oral hygiene and good periodontal health.

Exclusion criteria

1. Skeletal discrepancies. 2. Missing maxillary anterior teeth or any kind of tooth/root shape anomaly. 3. Patients with root resorption or impacted canines. 4. Previous history of orthodontic treatment. 5. Systemic disease interferes with orthodontic tooth movement. 6. History of trauma affecting the maxillary incisors. 7. Poor oral hygiene or periodontally compromised patient. 8. Endodontically treated upper anterior teeth.

Design outcomes

Primary

Measure	Time frame
Amount of root resorption	Up to 6 months or correction of deep bite
Marginal bone level changes	Up to 6 months or correction of deep bite

Secondary

Measure	Time frame
Amount of intrusion of maxillary incisors	Up to 6 months or correction of deep bite

Countries

Egypt

Contacts

CONTACTTaha S.S Hossameldin, MSc Candidate

tahahossameldin.3.209@azhar.edu.eg+201096667923

CONTACTHussein N.I Al khalifa, Professor, Vice Dean (Phd)

HusseinAlkhalifa.209@azhar.edu.eg+201090302704

STUDY_DIRECTORHussein N.I Al khalifa, Professor, Vice Dean (Phd)

Faculty of Dental medicine (Boys), Al-Azhar University, Cairo, Egypt

STUDY_DIRECTORRaafat E. Mohamed, Prof, Head of Department (Phd)