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Study on the Prediction of Regional Lymph Node Metastasis in Colorectal Cancer by Spectral CT Combined With MSI

Study on the Prediction of Regional Lymph Node Metastasis in Colorectal Cancer by Spectral CT Combined With MSI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07565831
Enrollment
260
Registered
2026-05-04
Start date
2025-08-04
Completion date
2026-12-31
Last updated
2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colo-rectal Cancer

Brief summary

Spectral CT was used to prospectively collect medical images and clinical data related to colorectal cancer, evaluate the effect of image quality in the diagnosis of colorectal cancer, and evaluate the application value in the accurate staging of colorectal cancer, so as to provide a more accurate clinical basis for diagnosis, promote the development of individualized treatment, and ultimately improve the prognosis of patients.

Interventions

DIAGNOSTIC_TESTInvestigating the role of spectral CT combined with MSI status in the diagnosis and treatment of colorectal cancer lymph nodes.

The CT scan is part of the standard treatment protocol.

Sponsors

Yunnan Cancer Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* (1) Undergo contrast-enhanced Quark energy spectral CT examination of the lower abdomen/pelvis within 1 week before treatment;(2) MSI status confirmed;(3) Age \>18 years;(4) Patients with suspected colorectal cancer;(5) Patients who provided informed consent.

Exclusion criteria

* (1) Severe cardiac, pulmonary, or renal insufficiency;(2) Allergy to iodine-based contrast agents;(3) Inability to cooperate during the CT examination;(5) Poor image quality from Quark spectral CT scans;(6) Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frameDescription
Pathological TNM staging1 dayPathological examination information: The pathology results using surgery/biopsy data are the gold standard, and the depth of tumor invasion, lymph node metastasis, and distant metastasis are recorded

Countries

China

Contacts

STUDY_DIRECTORLianhua Ye

Ethics Committee of Yunnan Provincial Cancer Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 5, 2026