Facial Aging, Skin Aging, Skin Hydration, Transepidermal Water Loss
Conditions
Keywords
bioimpedance, BT-Analyze, Glogau scale, cosmetology, anti-aging, skin moisture
Brief summary
This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida. Skin moisture will be measured at seven points on the face using the BT-Analyze device. Photographs will be taken and evaluated by a blinded expert cosmetologist using a standard aging scoring system. The study will determine whether women with lower skin hydration tend to show more visible signs of aging.
Detailed description
Skin hydration is maintained through hyaluronic acid, natural moisturizing factor (NMF), and the lipid barrier of the stratum corneum. Dehydration activates matrix metalloproteinases (MMPs) which degrade collagen and elastin, accelerating visible aging. This cross-sectional observational study will enroll 30 women in three age groups (30-40, 40-50, and 50-60 years). Hydration will be assessed using BT-Analyze across seven facial zones. The primary outcome is the Spearman rank correlation between mean hydration score and modified Glogau visual aging score (0-18 points). Covariates include age, Fitzpatrick skin type, daily water intake, menopausal status, and skincare habits.
Interventions
OTHERBT-Analyze Bioimpedance Measurement
Non-invasive skin hydration measurement using BT-Analyze bioimpedance device at seven standardized facial zones. No therapeutic intervention is administered.
Sponsors
IAS Skin Care
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Female, aged 30 to 60 years Willing to attend one study visit without makeup No cosmetics applied for at least 4 hours prior to the visit Able to acclimate in controlled indoor environment for 20 minutes Signed written informed consent
Exclusion criteria
Active dermatological conditions (eczema, psoriasis, rosacea in flare) Injectable cosmetic procedures within the past 6 months Systemic medications affecting skin condition (oral retinoids, systemic corticosteroids) Pregnancy or lactation Uncontrolled systemic conditions known to significantly affect skin (e.g., uncontrolled diabetes mellitus)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spearman Correlation Between BT-Analyze Mean Score and Modified Glogau Visual Aging Score | At single study visit (Day 1) | Spearman rank correlation coefficient (rs) between mean BT-Analyze hydration score (mean of seven facial zones, 0-65 units) and total modified Glogau visual aging score (0-18 points) assessed by a blinded expert cosmetologist. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BT-Analyze Score Comparison Across Age Groups | At single study visit (Day 1) | Kruskal-Wallis comparison of mean BT-Analyze hydration scores between three age groups (30-40, 40-50, 50-60 years). |
Countries
United States
Outcome results
None listed